Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24963540 | 0.74 | LMNA (0.47) | KMT2AMAPK1LMNAMEN1SMN1; SMN2 | |
| SCHEMBL24963385 | 0.73 | LMNA (0.43) | KMT2ANT5EMAPK1LMNAMEN1 | |
| SCHEMBL24964931 | 0.72 | PIK3CA (0.51) | KMT2AMAPK1LMNAMEN1SMN1; SMN2 | |
| SCHEMBL24951261 | 0.71 | MAPT (0.49) | LMNASMN1; SMN2PTGS1PTGS2MAPT | |
| SCHEMBL18657400 | 0.70 | LMNA (0.59) | MAPK1LMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL15884550 | 0.68 | NAPRT (0.37) | KMT2AMAPK1LMNAMEN1SMN1; SMN2 | |
| SCHEMBL23410460 | 0.68 | KMT2A (0.64) | KMT2ANT5EMAPK1LMNAMEN1 | |
| SCHEMBL1156055 | 0.67 | LMNA (0.63) | KMT2ANT5EMAPK1LMNAMEN1 | |
| SCHEMBL5199645 | 0.67 | CES2 (0.73) | KMT2ANT5EMAPK1LMNAMEN1 | |
| 4-Chloro-Benzoic Acid SCHEMBL28828177 | 0.66 | TSHR (0.74) | KMT2ANT5EMAPK1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004280-A1 | SELECTIVE PYRAZOLE LRRK2 INHIBITORS AND METHODS FOR USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-01-26 | — | — | WO | disclosed |