Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 12/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24840948 | 0.84 | SLC16A3 (0.53) | APPPGRTERTALDH1A1TSHR | |
| SCHEMBL22289661 | 0.79 | DYRK1A (0.41) | DYRK1AAPPPGRALDH1A1ALOX15 | |
| SCHEMBL16284307 | 0.78 | SLC16A3 (0.48) | APPPGRALDH1A1ALOX15HSD17B10 | |
| SCHEMBL23172755 | 0.76 | APP (0.43) | APPPGRTERTALDH1A1TSHR | |
| SCHEMBL9947486 | 0.75 | APP (0.66) | APPPGRALDH1A1TSHRRAB9A | |
| SCHEMBL27448031 | 0.74 | LOXL2 (0.53) | APPPGRTERTSLC16A3MEN1 | |
| SCHEMBL14197740 | 0.74 | CYP2A6 (0.57) | APPPGR | |
| SCHEMBL170369 | 0.74 | ALDH1A1 (0.55) | DYRK1AAPPALDH1A1 | |
| SCHEMBL15398186 | 0.73 | PGR (0.76) | PGRALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL22311492 | 0.72 | PAX8 (0.41) | DYRK1AAPPALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001061-A1 | CDK7 SELECTIVE INHIBITORS AS ANTICANCER AGENTS | JINGRUI BIOPHARMA CO., LTD. (CN) | 2023-01-26 | — | — | WO | disclosed |