Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250232 | 0.97 | EGLN1 (0.47) | EGLN1RAB9AL3MBTL1TSHRCASP3 | |
| SCHEMBL250677 | 0.82 | POLB (0.44) | EGLN1RAB9AL3MBTL1TSHRCASP3 | |
| SCHEMBL249063 | 0.80 | PRKCA (0.50) | EGLN1RAB9AL3MBTL1KMT2AMMP1 | |
| SCHEMBL249835 | 0.79 | RAB9A (0.59) | RAB9AL3MBTL1TSHRKMT2AMEN1 | |
| SCHEMBL125290 | 0.78 | LMNA (0.51) | RAB9AL3MBTL1TSHRKMT2AMEN1 | |
| SCHEMBL619376 | 0.78 | LIPG (0.49) | EGLN1KMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL28912380 | 0.77 | TSHR (0.52) | RAB9ATSHRKMT2AMEN1HSP90AA1 | |
| SCHEMBL249442 | 0.77 | CYP1A2 (0.45) | EGLN1RAB9AL3MBTL1TSHRPOLB | |
| SCHEMBL10233174 | 0.74 | ALDH1A1 (0.49) | L3MBTL1TSHRKMT2AMEN1HSP90AA1 | |
| SCHEMBL5297257 | 0.72 | ALDH1A1 (0.58) | RAB9AL3MBTL1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097410-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | RESPIRATORIUS AB (SE) | 2010-09-02 | — | — | WO | disclosed |