SCHEMBL24969296

SCHEMBL24969296

Clc1cccc2c1oc1ccc(-c3ccccc3)cc12

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.49
CSNK2A2 P19784 1/20 0.49
CSNK2B P67870 1/20 0.49
PIM3 Q86V86 1/20 0.49
PIM2 Q9P1W9 1/20 0.49
TTR P02766 4/20 0.49
AHR P35869 6/20 0.49
PLA2G2A P14555 4/20 0.47
PLA2G4A P47712 4/20 0.47
PLA2G10 O15496 1/20 0.44
ALOX5 P09917 1/20 0.40
ESR2 Q92731 1/20 0.40
PRKDC P78527 1/20 0.39
PGR P06401 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31385551 1.00 PIM1 (0.49) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL25567828 1.00 PIM1 (0.49) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL23203877 0.89 PIM1 (0.46) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL21191836 0.88 PIM1 (0.47) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL29693288 0.87 TTR (0.49) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL24969295 0.87 TTR (0.49) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL21645332 0.87 TTR (0.47) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL21645316 0.85 PIM1 (0.44) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL22137189 0.84 PLA2G2A (0.47) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL25567907 0.83 ALOX5 (0.54) PIM1CSNK2A2CSNK2BPIM3PIM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4219484-A1 ORGANIC LIGHT-EMITTING DEVICE, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT Materials Co., Ltd. (KR) 2023-08-02 EP disclosed
US-20230232717-A1 ORGANIC LIGHT-EMITTING DEVICE, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHTEMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-07-20 US disclosed
US-20230232717-A1 ORGANIC LIGHT-EMITTING DEVICE, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHTEMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-07-20 US disclosed
CN-116332768-A Light emitting element and amine compound used therefor 三星显示有限公司 2023-06-27 CN disclosed
CN-116283861-A Amine compound and light emitting device including the same 三星显示有限公司 2023-06-23 CN disclosed
US-20230200236-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20230200236-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20230200220-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20230200220-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20230200220-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
WO-2023003234-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2023-01-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230232717-A1 ORGANIC LIGHT-EMITTING DEVICE, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHTEMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE CYBA, AOX1, CYP1A1 PIM1 1002/4885CSNK2A2 2485/4885CSNK2B 2383/4885
US-20230200236-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR LIGHT EMITTING DEVICE CHRM1, MAOA, GRIN1 PIM1 3173/4885CSNK2A2 1876/4885CSNK2B 2288/4885
US-20230200220-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME MAOA, NFE2L2, SLC1A2 PIM1 4398/4885CSNK2A2 1011/4885CSNK2B 1754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.