Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28296563 | 0.77 | ABCC4 (0.35) | ABCC4MAPTALDH1A1LMNAFAAH | |
| SCHEMBL5402287 | 0.77 | ALDH1A1 (0.48) | ABCC4MAPTALDH1A1LMNAFAAH | |
| SCHEMBL18863964 | 0.76 | TSHR (0.40) | ABCC4MAPTALDH1A1LMNAFAAH | |
| SCHEMBL873301 | 0.74 | FAAH (0.51) | ALDH1A1LMNAFAAH | |
| SCHEMBL7199512 | 0.70 | — | — | |
| SCHEMBL71305 | 0.69 | — | — | |
| SCHEMBL22092279 | 0.68 | — | — | |
| SCHEMBL9234835 | 0.67 | THRB (0.39) | ALDH1A1 | |
| SCHEMBL22493543 | 0.67 | — | — | |
| SCHEMBL27319730 | 0.67 | FAAH (0.41) | ALDH1A1LMNAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000026177-A1 | SYNTHESIS OF ETHYL BROMOPYRUVATE | GREAT LAKES CHEMICAL CORPORATION (US) | 2000-05-11 | — | — | WO | claimed |
| EP-0202157-B1 | N-SUBSTITUTED 2-AMINO-THIAZOLES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE | LABORATOIRES CHAUVIN S.A. (FR) | 1989-08-23 | — | — | EP | claimed |
| EP-0089678-B1 | NOVEL 2-BETA-D-RIBOFURANOSYLSELENAZOLE-4-CARBOXAMIDE COMPOUNDS AND METHODS FOR THEIR PRODUCTION | BRIGHAM YOUNG UNIVERSITY (US) | 1986-09-24 | — | — | EP | claimed |
| US-20220089542-A1 | PROCESS FOR PREPARATION OF ALDEHYDE SCAVENGER AND INTERMEDIATES | ALDEYRA THERAPEUTICS, INC. | 2022-03-24 | — | — | US | disclosed |
| WO-2020223717-A1 | PROCESS FOR PREPARATION OF ALDEHYDE SCAVENGER AND INTERMEDIATES | ALDEYRA THERAPEUTICS, INC. (US) | 2020-11-05 | — | — | WO | disclosed |
| US-9890162-B2 | Bicyclic aromatic carboxamide compounds useful as pim kinase inhibitors | INCYTE CORPORATION (US) | 2018-02-13 | — | — | US | disclosed |
| EP-2943485-B1 | BICYCLIC AROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE HOLDINGS CORP (US) | 2017-09-20 | — | — | EP | disclosed |
| US-20170253587-A1 | BICYCLIC AROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE CORPORATION | 2017-09-07 | — | — | US | disclosed |
| US-9676750-B2 | Bicyclic aromatic carboxamide compounds useful as pim kinase inhibitors | INCYTE CORPORATION (US) | 2017-06-13 | — | — | US | disclosed |
| US-9580418-B2 | Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors | INCYTE CORPORATION (US) | 2017-02-28 | — | — | US | disclosed |
| US-20160137626-A1 | BICYCLIC AROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE CORPORATION (US) | 2016-05-19 | — | — | US | disclosed |
| US-8524707-B2 | Bicyclic pyrazoles as protein kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2013-09-03 | — | — | US | disclosed |
| EP-2373664-B1 | BICYCLIC PYRAZOLES AS PROTEIN KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2013-06-12 | — | — | EP | disclosed |
| US-20110257165-A1 | BICYCLIC PYRAZOLES AS PROTEIN KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2011-10-20 | — | — | US | disclosed |
| EP-2373664-A1 | BICYCLIC PYRAZOLES AS PROTEIN KINASE INHIBITORS | Nerviano Medical Sciences S.r.l. (IT) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010070060-A1 | BICYCLIC PYRAZOLES AS PROTEIN KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2010-06-24 | — | — | WO | disclosed |
| US-20040180936-A1 | Heterocyclic compounds and their use as medicaments | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIEQUES (S.C.R.A.S.) | 2004-09-16 | — | — | US | disclosed |
| US-6747024-B1 | INHIBITING CALPAIN AND/OR REACTIVE OXYGEN SPECIES IN WARM-BLOODED ANIMALS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-06-08 | — | — | US | disclosed |
| US-4785008-A | ANTIINFLAMMATORY AGENTS | LABORATOIRES CHAUVIN-BLACHE (FR) | 1988-11-15 | — | — | US | disclosed |
| US-4450169-A | PESTICIDES; NEMATOCIDES; FUNGICIDES; MITICIDES; REPELLANTS | ROUSSEL UCLAF (FR) | 1984-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137626-A1 | BICYCLIC AROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | PIM1, PIM2, PIM3 | ABCC4 1973/4885MAPT 3113/4885ALDH1A1 2531/4885 |
| US-20040180936-A1 | Heterocyclic compounds and their use as medicaments | CAPN1, CAPN2, CAPNS1 | ABCC4 1650/4885MAPT 1874/4885ALDH1A1 3628/4885 |
| US-20220089542-A1 | PROCESS FOR PREPARATION OF ALDEHYDE SCAVENGER AND INTERMEDIATES | ALDH2, AOX1, ALDH1A1 | ABCC4 1974/4885MAPT 3924/4885ALDH1A1 3/4885 |
| US-20110257165-A1 | BICYCLIC PYRAZOLES AS PROTEIN KINASE INHIBITORS | MAP3K19, MAP4K3, MAP3K15 | ABCC4 2106/4885MAPT 2667/4885ALDH1A1 2877/4885 |
| US-20170253587-A1 | BICYCLIC AROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | PIM1, PIM2, PIM3 | ABCC4 1973/4885MAPT 3113/4885ALDH1A1 2531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.