Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8412922 | 0.81 | ADRB2 (0.48) | CA1CA2DNM1ADRB2ADRB1 | |
| SCHEMBL309239 | 0.78 | — | — | |
| SCHEMBL8076684 | 0.75 | — | — | |
| SCHEMBL19442182 | 0.75 | — | — | |
| SCHEMBL308837 | 0.75 | — | — | |
| SCHEMBL27605114 | 0.75 | ADRB2 (0.42) | CA1CA2DNM1ADRB2ADRB1 | |
| SCHEMBL577776 | 0.73 | TSHR (0.39) | — | |
| SCHEMBL21026920 | 0.73 | — | — | |
| SCHEMBL22268437 | 0.73 | — | — | |
| SCHEMBL308919 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276095-A2 | PROCESSES FOR PREPARING ASK1 INHIBITORS | Gilead Sciences, Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| EP-3693366-B1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES INC (US) | 2023-06-28 | — | — | EP | disclosed |
| US-20220135527-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES, INC. | 2022-05-05 | — | — | US | disclosed |
| US-11261161-B2 | Processes for preparing ASK1 inhibitors | GILEAD SCIENCES, INC. (US) | 2022-03-01 | — | — | US | disclosed |
| EP-3237404-B1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES INC (US) | 2020-11-11 | — | — | EP | disclosed |
| US-20200283393-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES, INC. | 2020-09-10 | — | — | US | disclosed |
| EP-3693366-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | Gilead Sciences, Inc. (US) | 2020-08-12 | — | — | EP | disclosed |
| US-10604490-B2 | Processes for preparing ASK1 inhibitors | GILEAD SCIENCES, INC. (US) | 2020-03-31 | — | — | US | disclosed |
| US-20180022708-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES, INC. | 2018-01-25 | — | — | US | disclosed |
| EP-2072496-B1 | METHOD FOR PRODUCING HIGH-PURITY QUATERNARY AMMONIUM SALT | OTSUKA CHEMICAL CO LTD (JP) | 2017-11-15 | — | — | EP | disclosed |
| US-8029690-B2 | Process for production of highly pure quaternary ammonium salt | OTSUKA CHEMICAL CO., LTD. (JP) | 2011-10-04 | — | — | US | disclosed |
| US-20100044617-A1 | Method for producing high-purity quaternary ammonium salt | STELLA CHEMIFA CORPORATION (JP) | 2010-02-25 | — | — | US | disclosed |
| US-20090272933-A1 | Process for production of highly pure quaternary ammonium salt | STELLA CHEMIFA CORPORATION (JP) | 2009-11-05 | — | — | US | disclosed |
| EP-2098518-A1 | PROCESS FOR PRODUCTION OF HIGHLY PURE QUATERNARY AMMONIUM SALT | Otsuka Chemical Co., Ltd. (JP) | 2009-09-09 | — | — | EP | disclosed |
| EP-2072496-A1 | METHOD FOR PRODUCING HIGH-PURITY QUATERNARY AMMONIUM SALT | Otsuka Chemical Co., Ltd. (JP) | 2009-06-24 | — | — | EP | disclosed |
| CN-101353341-A | Colorant reacted by oxyalkylene-substituted aminophenol intermediate | MILLIKEN & CO (US) | 2009-01-28 | — | — | CN | disclosed |
| CN-100424135-C | Colorants produced by reaction of oxyalkylene-substituted aminophenol intermediate | MILLIKEN & CO (US) | 2008-10-08 | — | — | CN | disclosed |
| CN-1847322-A | Colorants produced by reaction of oxyalkylene-substituted aminophenol intermediate | MILLIKEN & CO (US) | 2006-10-18 | — | — | CN | disclosed |
| CN-1263728-C | Oxyalkylene-substituted aminophenol intermediates | MILLIKEN & CO (US) | 2006-07-12 | — | — | CN | disclosed |
| CN-1351583-A | Oxyalkylene-substituted aminophenol intermediates | MILLIKEN & CO (US) | 2002-05-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283393-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | MAP3K1, MAP3K6, MAP3K7 | CA1 4790/4885CA2 4680/4885DNM1 1048/4885 |
| US-10604490-B2 | Processes for preparing ASK1 inhibitors | MAP3K1, MAP3K6, MAP3K7 | CA1 4790/4885CA2 4680/4885DNM1 1048/4885 |
| US-11261161-B2 | Processes for preparing ASK1 inhibitors | MAP3K1, MAP3K6, MAP3K7 | CA1 4790/4885CA2 4680/4885DNM1 1048/4885 |
| US-20180022708-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | MAP3K1, MAP3K6, MAP3K7 | CA1 4790/4885CA2 4680/4885DNM1 1048/4885 |
| US-20220135527-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | MAP3K1, MAP3K6, MAP3K7 | CA1 4790/4885CA2 4680/4885DNM1 1048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.