SCHEMBL249752

SCHEMBL249752

CN1C(=O)NC(=O)C(O)C1=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1263088 0.73 MEN1 (0.37) TSHR
SCHEMBL6968100 0.68
SCHEMBL17408807 0.68
SCHEMBL2851785 0.68 ALDH1A1 (0.41)
SCHEMBL6967195 0.66 ALDH1A1 (0.43)
SCHEMBL2848935 0.66 ALDH1A1 (0.40) TSHR
SCHEMBL5956026 0.65
SCHEMBL5956305 0.65
SCHEMBL5956012 0.65
SCHEMBL10746176 0.64 MAPT (0.48) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630851-B2 Polynucleotide modification methods OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-05-19 US claimed
US-12084715-B1 Methods and systems for reducing artifactual antisense products 10X GENOMICS, INC. (US) 2024-09-10 US claimed
US-20220186274-A1 POLYNUCLEOTIDE MODIFICATION METHODS OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2022-06-16 US claimed
US-11186857-B2 Polynucleotide modification methods OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2021-11-30 US claimed
US-20200131549-A1 POLYNUCLEOTIDE MODIFICATION METHODS OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2020-04-30 US claimed
EP-3033435-B1 METHOD FOR FRAGMENTING NUCLEIC ACID BY MEANS OF TRANSPOSASE OXFORD NANOPORE TECH LTD (GB) 2019-07-24 EP claimed
EP-3033435-A1 METHOD Oxford Nanopore Technologies Limited (GB) 2016-06-22 EP claimed
WO-2015022544-A1 METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2015-02-19 WO claimed
US-7811753-B2 Methods for repairing degraded DNA IBIS BIOSCIENCES, INC. (US) 2010-10-12 US claimed
US-7531306-B2 Nucleic acid hybridization methods GENEOHM SCIENCES, INC. (US) 2009-05-12 US claimed
EP-1689879-A4 NUCLEIC ACID HYBRIDIZATION METHODS GENEOHM SCIENCES INC (US) 2008-08-27 EP claimed
EP-1689879-A2 NUCLEIC ACID HYBRIDIZATION METHODS Geneohm Sciences, Inc. (US) 2006-08-16 EP claimed
WO-2006019784-A2 METHODS FOR REPAIRING DEGRADED DNA ISIS PHARMACEUTICALS, INC. (US) 2006-02-23 WO claimed
US-20060014154-A1 Methods for repairing degraded DNA IBIS BIOSCIENCES, INC. 2006-01-19 US claimed
US-20050176035-A1 Destabilization of hybridization via DNA N-glycosylase/uridine nucleosidase, insertion of probe; kits GENEOHM SCIENCE, INC. 2005-08-11 US claimed
WO-2005049848-A2 NUCLEIC ACID HYBRIDIZATION METHODS GENEOHM SCIENCES, INC. (US) 2005-06-02 WO claimed
US-12630851-B2 Polynucleotide modification methods OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-05-19 US disclosed
US-20260015392-A1 MUTANT CSGG PORES OXFORD NANOPORE TECHNOLOGIES PLC (BE) 2026-01-15 US disclosed
US-20030104459-A1 Multiplex PCR AFFYMETRIX, INC. 2003-06-05 US disclosed
WO-2003044177-A2 MULTIPLEX PCR PARALLELE BIOSCIENCE, INC. (US) 2003-05-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630851-B2 Polynucleotide modification methods PNP, NT5C3B, UNG TSHR 2677/4885
US-20260015392-A1 MUTANT CSGG PORES NPPA, AFG3L2, SCAMP3 TSHR 4138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.