Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10763451 | 0.85 | MAPT (0.42) | PIN1PLAUMAPTMAPK1TDP1 | |
| SCHEMBL24975433 | 0.82 | HTT (0.51) | MAPTMAPK1TDP1L3MBTL1RXRA | |
| SCHEMBL24975429 | 0.82 | RXRA (0.45) | LRRK2MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL30337545 | 0.80 | PIN1 (0.51) | PIN1PLAUMAPTMAPK1TDP1 | |
| SCHEMBL17270074 | 0.80 | PIN1 (0.51) | PIN1PLAUMAPTMAPK1TDP1 | |
| SCHEMBL6639288 | 0.78 | L3MBTL1 (0.51) | PIN1PLAUMAPTMAPK1TDP1 | |
| SCHEMBL30839874 | 0.78 | L3MBTL1 (0.51) | PIN1PLAUMAPTMAPK1TDP1 | |
| SCHEMBL22851668 | 0.78 | MRGPRX4 (0.43) | PIN1LRRK2MAPTMAPK1TDP1 | |
| SCHEMBL13195026 | 0.77 | LTA4H (0.49) | PIN1LTA4HMAPK14 | |
| SCHEMBL25382124 | 0.77 | DCPS (0.52) | MAPTMAPK1TDP1L3MBTL1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023005894-A1 | INHIBITOR COMPOUND FOR WNT PATHWAY | 杭州阿诺生物医药科技有限公司 | 2023-02-02 | — | — | WO | disclosed |