Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24975769 | 0.81 | L3MBTL1 (0.53) | L3MBTL1KMT2ACYP3A4KDM1ACXCR4 | |
| SCHEMBL24976021 | 0.81 | L3MBTL1 (0.53) | L3MBTL1KMT2ACYP3A4KDM1ACXCR4 | |
| SCHEMBL24977220 | 0.81 | L3MBTL1 (0.53) | L3MBTL1KMT2ACYP3A4KDM1ACXCR4 | |
| SCHEMBL25841821 | 0.76 | KMT2A (0.50) | L3MBTL1KMT2AALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL7475783 | 0.74 | SIGMAR1 (0.65) | KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL20781142 | 0.73 | CYP3A4 (0.46) | L3MBTL1KMT2ACYP3A4CXCR4ALDH1A1 | |
| SCHEMBL20773434 | 0.73 | CYP3A4 (0.46) | L3MBTL1KMT2ACYP3A4CXCR4ALDH1A1 | |
| SCHEMBL25530099 | 0.73 | CYP3A4 (0.46) | L3MBTL1KMT2ACYP3A4CXCR4ALDH1A1 | |
| SCHEMBL25530138 | 0.73 | CYP3A4 (0.46) | L3MBTL1KMT2ACYP3A4CXCR4ALDH1A1 | |
| SCHEMBL25530141 | 0.73 | CYP3A4 (0.46) | L3MBTL1KMT2ACYP3A4CXCR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | AMGEN INC. (US) | 2023-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | CYP3A7, CYP51A1, NT5C3B | L3MBTL1 4695/4885KMT2A 2971/4885CYP3A4 432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.