Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24977220 | 0.82 | L3MBTL1 (0.53) | ALDH1A1MEN1KMT2AKDM1AL3MBTL1 | |
| SCHEMBL24976021 | 0.82 | L3MBTL1 (0.53) | ALDH1A1MEN1KMT2AKDM1AL3MBTL1 | |
| SCHEMBL24975769 | 0.82 | L3MBTL1 (0.53) | ALDH1A1MEN1KMT2AKDM1AL3MBTL1 | |
| SCHEMBL24976393 | 0.81 | ALDH1A1 (0.51) | ALDH1A1EPHX2LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL29950234 | 0.77 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL24977312 | 0.77 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL27022355 | 0.73 | ALDH1A1 (0.71) | STSALDH1A1EPHX2LMNAMEN1 | |
| SCHEMBL24976091 | 0.71 | L3MBTL1 (0.42) | ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL31003008 | 0.71 | ALDH1A1 (0.48) | STSALDH1A1LMNAKMT2ATP53 | |
| SCHEMBL2710950 | 0.70 | PTPN2 (0.79) | STSALDH1A1EPHX2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | AMGEN INC. (US) | 2023-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | CYP3A7, CYP51A1, NT5C3B | STS 743/4885ALDH1A1 793/4885EPHX2 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.