SCHEMBL3082528

SCHEMBL3082528

CC(=O)OCc1ccc(C=O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.60
CYP3A4 P08684 1/20 0.47
ALDH5A1 P51649 1/20 0.45
ABAT P80404 1/20 0.45
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KMT2A Q03164 3/20 0.41
CYP2A6 P11509 2/20 0.41
IDH1 O75874 1/20 0.40
MEN1 O00255 1/20 0.40
EPHX2 P34913 1/20 0.40
NR1H4 Q96RI1 1/20 0.40
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
CA2 P00918 1/20 0.39
RAB9A P51151 1/20 0.39
CA12 O43570 1/20 0.39
AKR1B10 O60218 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E1501 SCHEMBL11503249 0.87 ALDH1A1 (0.76) ALDH1A1LMNASMN1; SMN2KMT2ACYP2A6
SCHEMBL132773 0.85 ALDH1A1 (0.78) ALDH1A1CYP3A4LMNAMAPTKMT2A
SCHEMBL4764759 0.85 ALDH1A1 (0.57) ALDH1A1CYP3A4LMNAMAPTHPGD
SCHEMBL10604973 0.84 ALDH1A1 (0.69) ALDH1A1CYP3A4LMNAKMT2AIDH1
SCHEMBL11315920 0.84 ALDH1A1 (0.69) ALDH1A1CYP3A4LMNAKMT2AIDH1
SCHEMBL1051823 0.83 ALDH1A1 (0.58) ALDH1A1CYP3A4LMNAMAPTKMT2A
SCHEMBL14230568 0.82 ALDH1A1 (0.62) ALDH1A1CYP3A4MAPTSMN1; SMN2KMT2A
SCHEMBL16800184 0.81 MET (0.47) ALDH1A1LMNAMAPTHPGDSMN1; SMN2
SCHEMBL13632581 0.81 ALDH1A1 (0.56) ALDH1A1CYP3A4LMNAMAPTSMN1; SMN2
SCHEMBL22322104 0.81 ALDH5A1 (0.45) ALDH1A1ALDH5A1ABATLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7022862-B2 Scalable synthesis of dipyrromethanes NORTH CAROLINA STATE UNIVERSITY (US) 2006-04-04 US claimed
CN-118878451-A Preparation method and application of cis-2, 3-disubstituted indoline compound 郑州大学 2024-11-01 CN disclosed
EP-2258804-B1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECH LTD (GB) 2012-08-22 EP disclosed
EP-2258804-B1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECH LTD (GB) 2012-08-22 EP disclosed
CN-1980600-B Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers UNIV NORTH CAROLINA 2011-08-10 CN disclosed
EP-2258804-A2 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2010-12-08 EP disclosed
US-7795802-B2 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2010-09-14 US disclosed
US-7718794-B2 Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers NORTH CAROLINA STATE UNIVERSITY (US) 2010-05-18 US disclosed
US-20080194839-A1 SYNTHESIS OF PORPHYRINS DESIGNED FOR ATTACHMENT TO ELECTROACTIVE SURFACES VIA ONE OR MORE CARBON TETHERS NORTH CAROLINA STATE UNIVERSITY (US) 2008-08-14 US disclosed
US-7378520-B2 Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers NORTH CAROLINA STATE UNIVERSITY (US) 2008-05-27 US disclosed
US-20030166810-A1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2003-09-04 US disclosed
US-6559256-B2 Luminescent film-forming solvent processible polymer for use in photoluminescent and electroluminescent devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2003-05-06 US disclosed
EP-1291406-A1 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2003-03-12 EP disclosed
US-20030008991-A1 POLYMERS FOR USE IN OPTICAL DEVICES CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2003-01-09 US disclosed
EP-0800563-B1 POLYMERS FOR USE IN OPTICAL DEVICES CAMBRIDGE DISPLAY TECH LTD (GB) 2000-07-12 EP disclosed
EP-1006169-A1 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2000-06-07 EP disclosed
EP-0800563-A1 POLYMERS FOR USE IN OPTICAL DEVICES Cambridge Display Technology Limited (GB) 1997-10-15 EP disclosed
WO-1996020253-A1 POLYMERS FOR USE IN OPTICAL DEVICES CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 1996-07-04 WO disclosed
US-4686229-A THROMBOEMBOLIC AND ISCHAEMIC DISORDERS BAYER AKTIENGESELLSCHAFT (DE) 1987-08-11 US disclosed
EP-0173204-A2 1,4-Dihydropyridines, process for their preparation and their pharmaceutical use BAYER AG (DE) 1986-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194839-A1 SYNTHESIS OF PORPHYRINS DESIGNED FOR ATTACHMENT TO ELECTROACTIVE SURFACES VIA ONE OR MORE CARBON TETHERS SCO2, PPOX, HCCS ALDH1A1 909/4885CYP3A4 641/4885ALDH5A1 210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.