Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19308899 | 0.86 | TSHR (0.38) | SCN8ATSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11319209 | 0.78 | CXCR4 (0.41) | TSHRSLC6A2SLC6A4SLC6A3KCNA5 | |
| SCHEMBL22984964 | 0.77 | TSHR (0.38) | TSHRSLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL6546934 | 0.75 | TAAR1 (0.44) | SLC6A2SLC6A4NR3C1PGRNR3C2 | |
| SCHEMBL8996448 | 0.73 | NR3C1 (0.41) | TSHRSLC6A2KCNH2NR3C1PGR | |
| SCHEMBL3249970 | 0.73 | MAOA (0.50) | TSHRSLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL21703726 | 0.73 | TSHR (0.37) | SCN8ATSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20385424 | 0.72 | ESR1 (0.46) | TSHRSLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL20385505 | 0.72 | ESR1 (0.46) | TSHRSLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL727640 | 0.72 | SOS2 (0.53) | SCN8ATSHRSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230012655-A1 | URIDINE DIPHOSPHATE DERIVATIVES, PRODRUGS, COMPOSITIONS AND USES THEREOF | UNIV TUFTS (US) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230012655-A1 | URIDINE DIPHOSPHATE DERIVATIVES, PRODRUGS, COMPOSITIONS AND USES THEREOF | UMPS, UPP1, UGDH | SCN8A 3004/4885TSHR 4504/4885SLC6A2 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.