Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 9/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | EIF4E | P06730 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30185130 | 1.00 | KMO (0.51) | KMOPTGER4PDE2AEIF4EMEN1 | |
| SCHEMBL24985736 | 0.88 | KMO (0.64) | KMOEIF4EMEN1KMT2ATTR | |
| SCHEMBL30185263 | 0.88 | KMO (0.64) | KMOEIF4EMEN1KMT2ATTR | |
| SCHEMBL30185181 | 0.86 | NOTUM (0.46) | KMOPTGER4EIF4E | |
| SCHEMBL24984484 | 0.86 | NOTUM (0.46) | KMOPTGER4EIF4E | |
| SCHEMBL24987042 | 0.86 | CYP11B2 (0.54) | KMOEIF4ECYP11B1CYP11B2 | |
| SCHEMBL30185117 | 0.86 | CYP11B2 (0.54) | KMOEIF4ECYP11B1CYP11B2 | |
| SCHEMBL24987032 | 0.84 | MAPT (0.49) | KMOEIF4EMEN1KMT2A | |
| SCHEMBL30185228 | 0.84 | MAPT (0.49) | KMOEIF4EMEN1KMT2A | |
| SCHEMBL24984511 | 0.78 | CASP1 (0.45) | KMOEIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | DOW AGROSCIENCES LLC (US) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | PDXK, DPYD, DDT | KMO 500/4885PTGER4 2462/4885PDE2A 2216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.