Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 9/20 | 0.64 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | EIF4E | P06730 | 4/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24985736 | 1.00 | KMO (0.64) | KMOTRPV3TTREIF4ECYP11B1 | |
| SCHEMBL30185117 | 0.89 | CYP11B2 (0.54) | KMOTRPV3EIF4ECYP11B1CYP11B2 | |
| SCHEMBL24987042 | 0.89 | CYP11B2 (0.54) | KMOTRPV3EIF4ECYP11B1CYP11B2 | |
| SCHEMBL30185130 | 0.88 | KMO (0.51) | KMOTTREIF4ECYP11B1CYP11B2 | |
| SCHEMBL24985200 | 0.88 | KMO (0.51) | KMOTTREIF4ECYP11B1CYP11B2 | |
| SCHEMBL24987032 | 0.85 | MAPT (0.49) | KMOEIF4EMEN1KMT2ANOTUM | |
| SCHEMBL30185228 | 0.85 | MAPT (0.49) | KMOEIF4EMEN1KMT2ANOTUM | |
| SCHEMBL24985709 | 0.84 | KMO (0.53) | KMOTRPV3EIF4EFAAHNOTUM | |
| SCHEMBL30185185 | 0.84 | KMO (0.53) | KMOTRPV3EIF4EFAAHNOTUM | |
| SCHEMBL24984511 | 0.81 | CASP1 (0.45) | KMOEIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | DOW AGROSCIENCES LLC (US) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | PDXK, DPYD, DDT | KMO 500/4885TRPV3 3090/4885TTR 2953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.