Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 3/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | CTSV | O60911 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24990242 | 0.84 | CTSV (0.44) | MPLGPR84CTSVCTSLHTR2A | |
| SCHEMBL24989606 | 0.83 | ADK (0.40) | MPLGPR84CTSVCTSLS1PR4 | |
| SCHEMBL24988674 | 0.74 | MPL (0.41) | MPLGPR84CTSVCTSLMAPT | |
| SCHEMBL24989509 | 0.74 | NPY5R (0.43) | MAPTRAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL29185311 | 0.71 | NPY5R (0.38) | S1PR4S1PR1S1PR5MAPTRAB9A | |
| SCHEMBL30848950 | 0.71 | NPY5R (0.38) | S1PR4S1PR1S1PR5MAPTRAB9A | |
| SCHEMBL24988657 | 0.69 | CTSV (0.43) | MPLGPR84CTSVCTSLRAB9A | |
| SCHEMBL30182908 | 0.69 | NPY5R (0.39) | MAPTRAB9AKDM4EMEN1KMT2A | |
| SCHEMBL24989505 | 0.67 | TLR8 (0.42) | MPLCTSVCTSLTLR8 | |
| SCHEMBL24988641 | 0.67 | TLR8 (0.42) | MPLCTSVCTSLTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023013994-A1 | NOVEL INDOLE DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 주식회사 미토이뮨테라퓨틱스 | 2023-02-09 | — | — | WO | disclosed |