Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.53 |
| ▸ | ACVR1 | Q04771 | 10/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 9/20 | 0.49 |
| ▸ | BMPR1A | P36894 | 3/20 | 0.49 |
| ▸ | ACVRL1 | P37023 | 3/20 | 0.49 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15047064 | 0.86 | CHRNB2 (0.64) | CHRNB2CHRNA4ADRB1ADRB2NCF1 | |
| SCHEMBL15498493 | 0.82 | MAPK10 (0.47) | ACVR1TGFBR1BMPR1AACVRL1KDR | |
| SCHEMBL5655553 | 0.81 | CHRNB2 (0.68) | CHRNB2CHRNA4HTR1AHTR7HTR3A | |
| SCHEMBL15245011 | 0.80 | ADRB1 (0.68) | TGFBR1HTR1AHTR7ADRB1ADRB2 | |
| SCHEMBL943026 | 0.79 | HTR7 (0.70) | ACVR1HTR1AHTR7ADRB1ADRB2 | |
| SCHEMBL1199578 | 0.79 | TGFBR1 (0.55) | CHRNB2CHRNA4ACVR1TGFBR1BMPR1A | |
| SCHEMBL24991124 | 0.78 | HTR1A (0.52) | ACVR1TGFBR1BMPR1AACVRL1HTR1A | |
| Hydrochloric Acid SCHEMBL943219 | 0.78 | HTR7 (0.68) | ACVR1HTR1AHTR7ADRB1ADRB2 | |
| SCHEMBL1198696 | 0.77 | ACVR1 (0.49) | CHRNB2CHRNA4ACVR1TGFBR1HTR1A | |
| SCHEMBL24989033 | 0.77 | CHRNB2 (0.49) | CHRNB2CHRNA4ACVR1TGFBR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011596-A1 | AMIDE COMPOUND AND USE THEREOF | 中国药科大学 | 2023-02-09 | — | — | WO | disclosed |