Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | HTT | P42858 | 4/20 | 0.66 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30173489 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1MAPTLMNAHTT | |
| SCHEMBL15401066 | 0.87 | KDR (0.74) | SMN1; SMN2MAPTLMNAHTTMMP2 | |
| SCHEMBL15401573 | 0.87 | MMP2 (0.76) | SMN1; SMN2ALDH1A1MAPTLMNAHTT | |
| SCHEMBL24993423 | 0.81 | ACHE (0.76) | SMN1; SMN2ALDH1A1MAPTLMNAHTT | |
| SCHEMBL16458931 | 0.81 | MMP2 (0.86) | SMN1; SMN2LMNAHTTMMP2MMP8 | |
| SCHEMBL30772149 | 0.80 | ACHE (0.66) | SMN1; SMN2ALDH1A1MAPTLMNAHTT | |
| SCHEMBL15403403 | 0.78 | ACHE (0.74) | SMN1; SMN2ALDH1A1MAPTLMNAHTT | |
| SCHEMBL30292503 | 0.78 | CYP1A1 (0.66) | SMN1; SMN2ALDH1A1MAPTLMNAHTT | |
| SCHEMBL24107596 | 0.78 | CYP1A1 (0.66) | SMN1; SMN2ALDH1A1MAPTLMNAHTT | |
| SCHEMBL2753589 | 0.78 | RAB9A (0.71) | SMN1; SMN2ALDH1A1MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115944635-A | Application of aminothiazole derivative in preparing medicine for treating immune inflammation | 宁波亿诺药业有限公司 | 2023-04-11 | — | — | CN | claimed |
| CN-115944635-A | Application of aminothiazole derivative in preparing medicine for treating immune inflammation | 宁波亿诺药业有限公司 | 2023-04-11 | — | — | CN | disclosed |
| WO-2023011609-A1 | USE OF AMINOTHIAZOLE DERIVATIVE IN PREPARATION OF IMMUNOLOGICAL INFLAMMATORY DRUG | 宁波亿诺药业有限公司 | 2023-02-09 | — | — | WO | disclosed |