Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | KDR | P35968 | 3/20 | 0.57 |
| ▸ | MMP2 | P08253 | 2/20 | 0.55 |
| ▸ | MMP8 | P22894 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15403403 | 0.92 | ACHE (0.74) | ACHESMN1; SMN2LMNARAB9AKDR | |
| SCHEMBL15401066 | 0.84 | KDR (0.74) | ACHESMN1; SMN2LMNAKDRMMP2 | |
| SCHEMBL30772149 | 0.83 | ACHE (0.66) | ACHESMN1; SMN2LMNARAB9AKDR | |
| SCHEMBL30173489 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNARAB9AKDRMMP2 | |
| SCHEMBL24993422 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNARAB9AKDRMMP2 | |
| SCHEMBL27821015 | 0.81 | MMP2 (0.82) | ACHESMN1; SMN2LMNARAB9AKDR | |
| SCHEMBL15401573 | 0.80 | MMP2 (0.76) | SMN1; SMN2LMNAKDRMMP2MMP8 | |
| SCHEMBL30772150 | 0.79 | MMP2 (0.86) | ACHESMN1; SMN2LMNAMMP2MMP8 | |
| SCHEMBL19956363 | 0.78 | HTR7 (0.58) | ACHELMNARAB9AMAPK1MAPT | |
| SCHEMBL18425338 | 0.76 | ACHE (0.66) | ACHESMN1; SMN2LMNARAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115944635-A | Application of aminothiazole derivative in preparing medicine for treating immune inflammation | 宁波亿诺药业有限公司 | 2023-04-11 | — | — | CN | claimed |
| CN-115944635-B | Application of aminothiazole derivative in preparation of immunity inflammation medicine | 宁波亿诺药业有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-115944635-A | Application of aminothiazole derivative in preparing medicine for treating immune inflammation | 宁波亿诺药业有限公司 | 2023-04-11 | — | — | CN | disclosed |
| WO-2023011609-A1 | USE OF AMINOTHIAZOLE DERIVATIVE IN PREPARATION OF IMMUNOLOGICAL INFLAMMATORY DRUG | 宁波亿诺药业有限公司 | 2023-02-09 | — | — | WO | disclosed |
| WO-2023011609-A1 | USE OF AMINOTHIAZOLE DERIVATIVE IN PREPARATION OF IMMUNOLOGICAL INFLAMMATORY DRUG | 宁波亿诺药业有限公司 | 2023-02-09 | — | — | WO | disclosed |