Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.66 |
| ▸ | MMP2 | P08253 | 2/20 | 0.65 |
| ▸ | MMP8 | P22894 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15403403 | 0.91 | ACHE (0.74) | ACHEMMP2MMP8MAPTTP53 | |
| SCHEMBL30173490 | 0.87 | MMP2 (0.78) | ACHEMMP2MMP8MAPTSMN1; SMN2 | |
| SCHEMBL27235580 | 0.87 | MMP2 (0.78) | ACHEMMP2MMP8MAPTSMN1; SMN2 | |
| SCHEMBL27821015 | 0.84 | MMP2 (0.82) | ACHEMMP2MMP8MAPTTP53 | |
| SCHEMBL24993423 | 0.83 | ACHE (0.76) | ACHEMMP2MMP8MAPTTP53 | |
| SCHEMBL15401066 | 0.81 | KDR (0.74) | ACHEMMP2MMP8MAPTSMN1; SMN2 | |
| SCHEMBL30173489 | 0.80 | SMN1; SMN2 (0.67) | MMP2MMP8MAPTSMN1; SMN2HTT | |
| SCHEMBL24993422 | 0.80 | SMN1; SMN2 (0.67) | MMP2MMP8MAPTSMN1; SMN2HTT | |
| SCHEMBL15401374 | 0.79 | MMP2 (1.00) | ACHEMMP2MMP8MAPTSMN1; SMN2 | |
| SCHEMBL16458931 | 0.79 | MMP2 (0.86) | MMP2MMP8SMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024027807-A1 | USE OF AMINOTHIAZOLE DERIVATIVE IN PREPARING DRUG FOR IMMUNOLOGICAL INFLAMMATION | 宁波亿诺药业有限公司 | 2024-02-08 | — | — | WO | disclosed |