SCHEMBL25001007

SCHEMBL25001007

CNC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](C)NC(=O)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 3/20 0.46
MMP1 P03956 3/20 0.46
LTA4H P09960 1/20 0.44
CPB2 Q96IY4 5/20 0.42
CTSK P43235 3/20 0.41
CTSS P25774 3/20 0.41
CTSL P07711 2/20 0.40
PSEN1 P49768 1/20 0.40
PSEN2 P49810 1/20 0.40
APH1B Q8WW43 1/20 0.40
NCSTN Q92542 1/20 0.40
APH1A Q96BI3 1/20 0.40
PSENEN Q9NZ42 1/20 0.40
CTSB P07858 1/20 0.40
CNR2 P34972 1/20 0.38
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37
GRIN1 Q05586 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19270372 0.80 MMP1 (0.51) MMP3MMP1CPB2CTSKCTSS
SCHEMBL10442107 0.78 MMP1 (0.48) MMP3MMP1LTA4HCPB2CTSK
SCHEMBL30833289 0.78 MMP2 (0.44) MMP3MMP1LTA4HCPB2CTSK
SCHEMBL25139551 0.77 NMT1 (0.42) MMP3CPB2MMP2
SCHEMBL25139728 0.77 NMT1 (0.42) MMP3CPB2MMP2
SCHEMBL24201037 0.77 LTA4H (0.49) LTA4HCPB2CTSKCTSSCTSL
SCHEMBL22133206 0.76 MMP1 (0.46) MMP3MMP1LTA4HCPB2CTSK
SCHEMBL5523004 0.76 CTSK (0.67) MMP3MMP1CPB2CTSKCTSS
SCHEMBL25139548 0.75 NMT1 (0.41) MMP3CPB2MMP2
SCHEMBL27284073 0.75 LTA4H (0.42) MMP3MMP1LTA4HCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023014360-A1 TREATMENT AND DIAGNOSIS OF IMMUNE DISORDERS RELATING TO ABERRANT IMMUNE CELLS OCTAGON THERAPEUTICS, INC. (US) 2023-02-09 WO disclosed