Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.44 |
| ▸ | MMP9 | P14780 | 4/20 | 0.44 |
| ▸ | MMP8 | P22894 | 4/20 | 0.44 |
| ▸ | MMP1 | P03956 | 7/20 | 0.43 |
| ▸ | MMP3 | P08254 | 6/20 | 0.43 |
| ▸ | MMP14 | P50281 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 2/20 | 0.36 |
| ▸ | MMP20 | O60882 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | MMP10 | P09238 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13274200 | 0.83 | MMP2 (0.68) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL6838745 | 0.83 | MMP2 (0.68) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL25001007 | 0.78 | MMP3 (0.46) | MMP2MMP9MMP1MMP3MMP14 | |
| SCHEMBL19270372 | 0.75 | MMP1 (0.51) | MMP1MMP3CPB2CTSSCTSK | |
| SCHEMBL7980261 | 0.73 | MMP2 (0.57) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL10442107 | 0.73 | MMP1 (0.48) | MMP1MMP3LTA4HCPB2CTSS | |
| SCHEMBL22133206 | 0.71 | MMP1 (0.46) | MMP1MMP3LTA4HCPB2CTSS | |
| SCHEMBL14321938 | 0.68 | LTA4H (0.43) | MMP9MMP1MMP3MMP14LTA4H | |
| SCHEMBL27284073 | 0.68 | LTA4H (0.42) | MMP1MMP3LTA4HCTSKMMP13 | |
| SCHEMBL6478513 | 0.68 | METAP2 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3642258-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2024-04-03 | — | — | EP | disclosed |