Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.73 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.63 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1304961 | 1.00 | HTR2A (0.73) | HTR2AGPR84TRPM8SLC6A4IDO1 | |
| SCHEMBL7842754 | 0.88 | GPR84 (0.63) | HTR2AGPR84SLC6A4HTR2CHTR1A | |
| SCHEMBL14511411 | 0.87 | HTR2A (0.77) | HTR2AGPR84TRPM8SLC6A4IDO1 | |
| SCHEMBL29527375 | 0.84 | HTR2A (1.00) | HTR2AGPR84TRPM8SLC6A4HTR2C | |
| SCHEMBL1305546 | 0.84 | HTR2A (1.00) | HTR2AGPR84TRPM8SLC6A4HTR2C | |
| SCHEMBL21292945 | 0.84 | HTR2A (1.00) | HTR2AGPR84TRPM8SLC6A4HTR2C | |
| SCHEMBL19068711 | 0.83 | HTR2A (0.72) | HTR2AGPR84TRPM8SLC6A4IDO1 | |
| SCHEMBL699380 | 0.83 | HTR2A (0.58) | HTR2ASLC6A4MTNR1AMTNR1BHTR2C | |
| SCHEMBL24328919 | 0.82 | SMN1; SMN2 (0.67) | HTR2AGPR84TRPM8SLC6A4MTNR1A | |
| SCHEMBL699832 | 0.81 | HTR2A (0.73) | HTR2AGPR84TRPM8SLC6A4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039846-A1 | COMPOUNDS AND METHODS OF USE | FERRO THERAPEUTICS INC (US) | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039846-A1 | COMPOUNDS AND METHODS OF USE | AIFM2, GPX4, GPX1 | HTR2A 3134/4885GPR84 3212/4885TRPM8 2310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.