Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ACACB | O00763 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25002922 | 0.86 | KMT2A (0.56) | KMT2AMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL25003142 | 0.84 | ALDH1A1 (0.53) | KMT2AMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL25002930 | 0.82 | RAB9A (0.49) | KMT2AMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25002901 | 0.81 | ADORA3 (0.49) | KMT2AMAPTSMN1; SMN2FPR2SCN9A | |
| SCHEMBL22027749 | 0.80 | KMT2A (0.42) | KMT2AMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL25002890 | 0.80 | MAP4K4 (0.51) | KMT2AMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL25002912 | 0.80 | PLA2G2A (0.48) | KMT2AMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL25002892 | 0.80 | NPC1 (0.52) | KMT2AMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL3140118 | 0.80 | SCN9A (0.57) | KMT2AMAPTMEN1FPR2SCN9A | |
| SCHEMBL14741986 | 0.80 | MAPT (0.48) | KMT2AMAPTSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010192-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | EUROFARMA LABORATÓRIOS S.A. (BR) | 2023-02-09 | — | — | WO | disclosed |