Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.45 |
| ▸ | PDE4A | P27815 | 3/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.45 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25003161 | 0.84 | FDPS (0.58) | FDPSPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL25002923 | 0.82 | FDPS (0.44) | FDPSPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL13188759 | 0.81 | DYRK1A (0.58) | FDPSLMNANPC1ALDH1A1RAB9A | |
| SCHEMBL25003934 | 0.80 | KDM4E (0.52) | FDPSPDE4DLMNANPC1ALDH1A1 | |
| SCHEMBL30800091 | 0.78 | ALDH1A1 (0.54) | LMNAALDH1A1MAPTACACB | |
| SCHEMBL7317661 | 0.78 | PARP10 (0.54) | PDE4DPDE4APDE4BPDE4CNPC1 | |
| SCHEMBL25003563 | 0.78 | KMO (0.52) | FDPSPDE4DABL1TYK2JAK3 | |
| SCHEMBL30951018 | 0.77 | FDPS (0.47) | FDPSPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL25003166 | 0.77 | FDPS (0.47) | FDPSPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL27237391 | 0.77 | FDPS (0.47) | FDPSPDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010192-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | EUROFARMA LABORATÓRIOS S.A. (BR) | 2023-02-09 | — | — | WO | disclosed |