Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | KDM6B | O15054 | 2/20 | 0.52 |
| ▸ | KDM5C | P41229 | 2/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.52 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.52 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.52 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.49 |
| ▸ | FDPS | P14324 | 3/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25003802 | 0.84 | FDPS (0.48) | JMJD6FDPSSCN10ALMNANPC1 | |
| SCHEMBL25003822 | 0.82 | KDM4E (0.63) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL25003563 | 0.81 | KMO (0.52) | FDPSLMNAPDE4DNPC1ALDH1A1 | |
| SCHEMBL25002908 | 0.80 | FDPS (0.57) | FDPSLMNAPDE4DNPC1ALDH1A1 | |
| SCHEMBL27997808 | 0.80 | KDM4E (0.69) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL7317661 | 0.79 | PARP10 (0.54) | EPHX2PDE4DNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8339652 | 0.78 | PARP10 (0.60) | EPHX2LMNANPC1ALDH1A1RAB9A | |
| SCHEMBL25002925 | 0.78 | NPC1 (0.59) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL25002923 | 0.78 | FDPS (0.44) | FDPSLMNAPDE4DNPC1ALDH1A1 | |
| SCHEMBL27237434 | 0.78 | MAPT (0.52) | KDM4ELMNANPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010192-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | EUROFARMA LABORATÓRIOS S.A. (BR) | 2023-02-09 | — | — | WO | disclosed |