Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29520004 | 0.85 | SCN9A (0.53) | TLR7SCN10AADORA3FPR2SCN9A | |
| SCHEMBL25002901 | 0.84 | ADORA3 (0.49) | KMT2ATLR7SCN10AADORA3FPR2 | |
| SCHEMBL25003826 | 0.83 | CA1 (0.54) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL25003126 | 0.82 | ALDH1A1 (0.51) | KMT2AMEN1ADORA3NPC1RAB9A | |
| SCHEMBL25003130 | 0.82 | ABL1 (0.60) | KMT2AMEN1TLR7SCN10ASCN9A | |
| SCHEMBL15104613 | 0.81 | CYP1A2 (0.46) | SCN10AADORA3FPR2SCN9ANPC1 | |
| SCHEMBL25003794 | 0.80 | PLK1 (0.49) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL25003134 | 0.80 | NPC1 (0.51) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL25003142 | 0.80 | ALDH1A1 (0.53) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL25003131 | 0.78 | MAP4K4 (0.55) | KMT2AMEN1RAB9AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010192-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | EUROFARMA LABORATÓRIOS S.A. (BR) | 2023-02-09 | — | — | WO | disclosed |