Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 6/20 | 0.44 |
| ▸ | HTR6 | P50406 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR5A | P47898 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27237944 | 0.79 | ALDH1A1 (0.38) | HTR6DRD3HTR1ADRD2CYP1A2 | |
| SCHEMBL5371667 | 0.78 | ADRB1 (0.45) | ADRB1HTR6DRD3HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL29176266 | 0.77 | LMNA (0.46) | ADRB1HTR6DRD3HTR1AHTR2A | |
| SCHEMBL6132755 | 0.74 | ADRB1 (0.51) | ADRB1HTR6DRD3HTR1AHTR2A | |
| SCHEMBL30885787 | 0.73 | NAMPT (0.43) | ALDH1A1LMNA | |
| SCHEMBL7026373 | 0.72 | DRD3 (0.40) | HTR6DRD3HTR1AHTR2ADRD2 | |
| SCHEMBL21995763 | 0.72 | ADRB1 (0.52) | ADRB1HTR6DRD3HTR1AHTR2A | |
| SCHEMBL5364978 | 0.71 | HTR6 (0.42) | ADRB1HTR6DRD3HTR1AHTR2A | |
| SCHEMBL5366562 | 0.71 | HTR2C (0.49) | ADRB1HTR6DRD3HTR1AHTR2A | |
| SCHEMBL5362857 | 0.71 | ADRB1 (0.47) | ADRB1HTR6DRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011608-A1 | REGULATOR CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海枢境生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |