Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.48 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25003934 | 0.84 | KDM4E (0.52) | FDPSSCN10ALMNANPC1ALDH1A1 | |
| SCHEMBL25003144 | 0.81 | KMO (0.51) | FDPSLMNANPC1ALDH1A1RAB9A | |
| SCHEMBL25003161 | 0.81 | FDPS (0.58) | FDPSLMNANPC1ALDH1A1RAB9A | |
| SCHEMBL25003821 | 0.80 | HDAC1 (0.64) | SCN10ALMNANPC1ALDH1A1RAB9A | |
| SCHEMBL25003135 | 0.79 | ALDH1A1 (0.61) | SCN10ALMNANPC1ALDH1A1RAB9A | |
| SCHEMBL25003827 | 0.79 | FDPS (0.46) | FDPSLMNANPC1ALDH1A1RAB9A | |
| SCHEMBL14161002 | 0.78 | PARP10 (0.61) | LMNANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL30171377 | 0.77 | MAPT (0.52) | LMNANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL27237434 | 0.77 | MAPT (0.52) | LMNANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL29828850 | 0.77 | KAT6A (0.60) | ALDH1A1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010192-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | EUROFARMA LABORATÓRIOS S.A. (BR) | 2023-02-09 | — | — | WO | disclosed |