SCHEMBL2500541

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2386705	0.91	USP2 (0.58)	USP2CASRTSHRHDAC1HDAC3
	SCHEMBL4224536	0.89	USP2 (0.56)	USP2CASRTSHRHDAC1HDAC3
	SCHEMBL2475852	0.88	OPRM1 (0.53)	USP2TSHRHDAC1HDAC3HDAC4
	SCHEMBL3832709	0.87	USP2 (0.55)	USP2CASRTSHRHSD17B10OPRM1
	SCHEMBL2473469	0.86	HDAC1 (0.61)	USP2TSHRHDAC1HDAC3HDAC4
	SCHEMBL2477227	0.86	OPRM1 (0.52)	TSHRHDAC1HDAC3HDAC4HDAC7
	SCHEMBL2477106	0.86	OPRM1 (0.54)	USP2TSHRHDAC1HDAC3HDAC4
	SCHEMBL2478140	0.86	HSD17B10 (0.52)	TSHRHDAC1HDAC3HDAC4HDAC7
	SCHEMBL2474112	0.86	TSHR (0.53)	TSHRHDAC1HDAC3HDAC4HDAC7
	SCHEMBL2497103	0.85	HDAC1 (0.50)	USP2TSHRHDAC1HDAC3HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.