Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 6/20 | 0.34 |
| ▸ | KCNJ5 | P48544 | 6/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 6/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23994607 | 0.86 | SLC6A4 (0.34) | CHEK1BTK | |
| SCHEMBL25004510 | 0.85 | CHEK1 (0.33) | CHEK1THRATHRB | |
| SCHEMBL23995261 | 0.74 | KCNJ6 (0.36) | KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL30224224 | 0.73 | HDAC1 (0.49) | CHEK1HDAC1HDAC6THRATHRB | |
| SCHEMBL23993198 | 0.73 | HDAC1 (0.49) | CHEK1HDAC1HDAC6THRATHRB | |
| SCHEMBL23995236 | 0.72 | THRA (0.32) | THRATHRB | |
| SCHEMBL30224480 | 0.72 | THRA (0.32) | THRATHRB | |
| SCHEMBL23995220 | 0.72 | THRA (0.32) | THRATHRB | |
| SCHEMBL9372428 | 0.70 | CA12 (0.47) | HDAC1HDAC6HDAC8 | |
| SCHEMBL25005705 | 0.68 | HTR3A (0.35) | KCNJ6KCNJ5KCNJ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | ENTPD5, ENTPD1, NT5E | KCNJ6 3297/4885KCNJ5 2932/4885KCNJ3 3311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.