Sugi Predict

Sugi Predict / Compounds / SCHEMBL2500559

SCHEMBL2500559

SCHEMBL2500559

CC(C)(C)[Si](C)(C)Oc1ccc(C(=O)c2ccc(O[Si](C)(C)C(C)(C)C)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 9/20 0.52
▸ PREP P48147 4/20 0.50
▸ KMT2A Q03164 2/20 0.47
▸ NPSR1 Q6W5P4 2/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ LMNA P02545 1/20 0.47
▸ MAPT P10636 1/20 0.47
▸ MAPK1 P28482 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ RXFP1 Q9HBX9 1/20 0.47
▸ CA12 O43570 2/20 0.45
▸ CA1 P00915 2/20 0.45
▸ CA9 Q16790 2/20 0.45
▸ FABP2 P12104 1/20 0.44
▸ PPARG P37231 1/20 0.44
▸ PPARA Q07869 1/20 0.44
▸ SLC22A12 Q96S37 1/20 0.44
▸ HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5280416 0.93 ELANE (0.57) ELANEPREPPPARGPPARA
SCHEMBL20364920 0.93 LMNA (0.53) ELANEPREPKMT2ANPSR1MEN1
SCHEMBL7012599 0.89 PREP (0.43) ELANEPREPKMT2ANPSR1MEN1
SCHEMBL3550962 0.87 MEN1 (0.49) ELANEPREPKMT2ANPSR1MEN1
SCHEMBL936407 0.87 MAPT (0.53) PREPKMT2ANPSR1LMNAMAPT
SCHEMBL6542930 0.87 CA1 (0.52) PREPKMT2ACA12CA1CA9
SCHEMBL18355840 0.86 PREP (0.41) ELANEPREPKMT2ANPSR1MEN1
SCHEMBL12339125 0.85 PARP10 (0.53) PREPKMT2ACA12CA1CA9
SCHEMBL7291293 0.85 PREP (0.45) ELANEPREPMAPTRAB9ACA12
SCHEMBL8906116 0.84 CA1 (0.56) PREPKMT2AMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608895-A1 HIGH TEMPERATURE DIELECTRIC POLYMERS AND FILMS The Scripps Research Institute (US) 2025-09-03 — — EP disclosed
WO-2024091675-A1 HIGH TEMPERATURE DIELECTRIC POLYMERS AND FILMS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-05-02 — — WO disclosed
EP-3310795-B1 POLYMERIZATION OF SILYL- AND FLUORO-CONTAINING MONOMERS SCRIPPS RESEARCH INST (US) 2021-06-16 — — EP disclosed
EP-3310795-B1 POLYMERIZATION OF SILYL- AND FLUORO-CONTAINING MONOMERS SCRIPPS RESEARCH INST (US) 2021-06-16 — — EP disclosed
US-10717820-B2 Polymerization of silyl- and fluoro-containing monomers THE SCRIPPS RESEARCH INSTITUTE (US) 2020-07-21 — — US disclosed
US-10717820-B2 Polymerization of silyl- and fluoro-containing monomers THE SCRIPPS RESEARCH INSTITUTE (US) 2020-07-21 — — US disclosed
US-20180194901-A1 POLYMERIZATION OF SILYL- AND FLUORO-CONTAINING MONOMERS THE SCRIPPS RESEARCH INSTITUTE 2018-07-12 — — US disclosed
US-20180194901-A1 POLYMERIZATION OF SILYL- AND FLUORO-CONTAINING MONOMERS THE SCRIPPS RESEARCH INSTITUTE 2018-07-12 — — US disclosed
US-9896547-B2 Polymerization method and polymers formed therewith THE SCRIPPS RESEARCH INSTITUTE (US) 2018-02-20 — — US disclosed
EP-2925803-B1 POLYMERIZATION METHOD AND POLYMERS FORMED THEREWITH SCRIPPS RESEARCH INST (US) 2017-11-29 — — EP disclosed
US-20150315340-A1 POLYMERIZATION METHOD AND POLYMERS FORMED THEREWITH THE SCRIPPS RESEARCH INSTITUTE 2015-11-05 — — US disclosed
EP-2925803-A1 POLYMERIZATION METHOD AND POLYMERS FORMED THEREWITH The Scripps Research Institute (US) 2015-10-07 — — EP disclosed
WO-2014089078-A1 POLYMERIZATION METHOD AND POLYMERS FORMED THEREWITH THE SCRIPPS RESEARCH INSTITUTE (US) 2014-06-12 — — WO disclosed
US-8030296-B2 Oestrogen-17-sulphamates as inhibitors of steroid sulphatase STERIX LIMITED (GB) 2011-10-04 — — US disclosed
US-20060281719-A1 Oestrogen-17-sulphamates as inhibitors of steroid sulphatase LLOYD POTTER BARRY V 2006-12-14 — — US disclosed
US-7119081-B2 Oestrogen-17-sulphamates as inhibitors of steroid sulphatase STERIX LIMITED (GB) 2006-10-10 — — US disclosed
US-20050227978-A1 Fibrosis inhibitor SUMITOMO PHARMACEUTICALS CO., LTD. (JP) 2005-10-13 — — US disclosed
US-20040209939-A1 Pyrrole derivatives SUMITOMO PHARMACEUTICALS CO., LTD. 2004-10-21 — — US disclosed
EP-0375457-B1 Cyclic ether derivatives ICI PLC (GB) 1994-03-16 — — EP disclosed
EP-0375457-A2 Cyclic ether derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-06-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050227978-A1 Fibrosis inhibitor SMAD3, MMP1, SMAD2 ELANE 125/4885PREP 430/4885KMT2A 3446/4885
US-20060281719-A1 Oestrogen-17-sulphamates as inhibitors of steroid sulphatase STS, SULT1E1, HSD17B11 ELANE 1737/4885PREP 1078/4885KMT2A 3525/4885
US-10717820-B2 Polymerization of silyl- and fluoro-containing monomers F12, ZYX, PYM1 ELANE 2022/4885PREP 4773/4885KMT2A 1328/4885
US-20040209939-A1 Pyrrole derivatives NCOA1, PKD1, NCOR1 ELANE 741/4885PREP 351/4885KMT2A 2623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.