SCHEMBL25008979

SCHEMBL25008979

O=Cc1cc(OCC(F)(F)C(F)(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.33
TRPV1 Q8NER1 1/20 0.33
MALT1 Q9UDY8 1/20 0.31
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24949712 0.81 TRPA1 (0.36) TRPA1TRPV1MALT1
SCHEMBL24948908 0.79 MALT1 (0.35) TRPA1TRPV1MALT1
SCHEMBL10119996 0.77 KDM4E (0.47) TRPA1TRPV1OPRL1
SCHEMBL14044796 0.75 ALDH1A1 (0.36) TRPA1TRPV1MALT1OPRL1
SCHEMBL3418088 0.73 DHODH (0.38) TRPA1TRPV1MALT1
SCHEMBL14337686 0.73 OPRL1 (0.38) TRPA1TRPV1OPRL1
SCHEMBL25082888 0.72 SLC16A3 (0.32) TRPA1MALT1OPRL1
SCHEMBL24949786 0.72 TRPA1 (0.36) TRPA1TRPV1MALT1OPRL1
SCHEMBL867603 0.72 TRPA1 (0.39) TRPA1TRPV1MALT1
SCHEMBL1762495 0.72 L3MBTL1 (0.40) TRPA1TRPV1MALT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023012081-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-09 WO disclosed