SCHEMBL2501568

SCHEMBL2501568

CN1c2ccc(-c3ccc4ccccc4c3)cc2Sc2cc(-c3ccc4ccccc4c3)ccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 7/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
MEN1 O00255 1/20 0.50
ADRA2A P08913 1/20 0.50
ADRA2B P18089 1/20 0.50
ADRA2C P18825 1/20 0.50
CHRM3 P20309 1/20 0.50
SLC6A2 P23975 1/20 0.50
HTR2C P28335 1/20 0.50
SLC6A4 P31645 1/20 0.50
DRD3 P35462 1/20 0.50
HTR2B P41595 1/20 0.50
KMT2A Q03164 1/20 0.50
MAOA P21397 1/20 0.50
AKT1 P31749 1/20 0.44
SNCA P37840 3/20 0.43
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
MAPT P10636 2/20 0.42
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7170967 0.84 MAOA (0.73) NOX1L3MBTL1MEN1ADRA2AADRA2B
SCHEMBL2493673 0.84 MAOA (0.55) NOX1L3MBTL1MEN1ADRA2AADRA2B
SCHEMBL12170796 0.81 MAOA (0.56) NOX1L3MBTL1MEN1ADRA2AADRA2B
SCHEMBL29634104 0.79 MAOA (0.66) NOX1L3MBTL1MEN1ADRA2AADRA2B
SCHEMBL16810786 0.79 MAOA (0.66) NOX1L3MBTL1MEN1ADRA2AADRA2B
SCHEMBL31067294 0.79 SNCA (0.47) NOX1L3MBTL1MEN1ADRA2AADRA2B
SCHEMBL12793430 0.79 MAOA (0.70) NOX1L3MBTL1MEN1ADRA2AADRA2B
SCHEMBL19649400 0.78 NOX1 (0.49) NOX1L3MBTL1MEN1ADRA2AADRA2B
SCHEMBL2503713 0.78 NOX1 (0.45) NOX1L3MBTL1MEN1ADRA2AADRA2B
SCHEMBL22115454 0.77 NOX1 (0.49) NOX1L3MBTL1MEN1ADRA2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1817806-B1 PHENOTHAZINES-S-OXIDES AND S,S-DIOXIDES AS hole and excitonblockers for OLEDs BASF SE (DE) 2014-07-30 EP disclosed
EP-1817806-B1 PHENOTHAZINES-S-OXIDES AND S,S-DIOXIDES AS hole and excitonblockers for OLEDs BASF SE (DE) 2014-07-30 EP disclosed
US-8029919-B2 Phenothiazines, S-oxides, and S,S-dioxides as well as phenoxazines as emitters for OLEDs BASF AKTIENGESELLSCHAFT (DE) 2011-10-04 US disclosed
US-8029919-B2 Phenothiazines, S-oxides, and S,S-dioxides as well as phenoxazines as emitters for OLEDs BASF AKTIENGESELLSCHAFT (DE) 2011-10-04 US disclosed
US-8029919-B2 Phenothiazines, S-oxides, and S,S-dioxides as well as phenoxazines as emitters for OLEDs BASF AKTIENGESELLSCHAFT (DE) 2011-10-04 US disclosed
US-20100308714-A1 Phenothiazines, S-Oxides, And S,S-Dioxides As Well As Phenoxazines As Emitters For Oleds BASF AKTIENGESELLSCHAFT (DE) 2010-12-09 US disclosed
US-20100308714-A1 Phenothiazines, S-Oxides, And S,S-Dioxides As Well As Phenoxazines As Emitters For Oleds BASF AKTIENGESELLSCHAFT (DE) 2010-12-09 US disclosed
US-20100308714-A1 Phenothiazines, S-Oxides, And S,S-Dioxides As Well As Phenoxazines As Emitters For Oleds BASF AKTIENGESELLSCHAFT (DE) 2010-12-09 US disclosed
US-20080018238-A1 Use Of Phenothiazine-S-Oxides And Phenothiazine -S,S-Dioxides In The Form Of Matrix Materials For Organic Light-Emitting Diodes BASF AKTIENGESELLSCHAFT (DE) 2008-01-24 US disclosed
US-20080018238-A1 Use Of Phenothiazine-S-Oxides And Phenothiazine -S,S-Dioxides In The Form Of Matrix Materials For Organic Light-Emitting Diodes BASF AKTIENGESELLSCHAFT (DE) 2008-01-24 US disclosed
US-20080018238-A1 Use Of Phenothiazine-S-Oxides And Phenothiazine -S,S-Dioxides In The Form Of Matrix Materials For Organic Light-Emitting Diodes BASF AKTIENGESELLSCHAFT (DE) 2008-01-24 US disclosed
EP-1817806-A1 PHENOTHAZINES, -S-OXIDES, AND S,S-DIOXIDES AS WELL AS PHENOXAZINES AS EMITTERS FOR OLEDS BASF AKTIENGESELLSCHAFT (DE) 2007-08-15 EP disclosed
EP-1817805-A1 USE OF PHENOTHIAZINE-S-OXIDES AND PHENOTHIAZINE -S,S-DIOXIDES IN THE FORM OF MATRIX MATERIALS FOR ORGANIC LIGHT-EMITTING DIODES BASF AKTIENGESELLSCHAFT (DE) 2007-08-15 EP disclosed
WO-2006056465-A1 PHENOTHIAZINES, -S-OXIDES, AND S,S-DIOXIDES AS WELL AS PHENOXAZINES AS EMITTERS FOR OLEDS BASF AKTIENGESELLSCHAFT (DE) 2006-06-01 WO disclosed
WO-2006056416-A1 USE OF PHENOTHIAZINE-S-OXIDES AND PHENOTHIAZINE -S,S-DIOXIDES IN THE FORM OF MATRIX MATERIALS FOR ORGANIC LIGHT-EMITTING DIODES BASF AKTIENGESELLSCHAFT (DE) 2006-06-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100308714-A1 Phenothiazines, S-Oxides, And S,S-Dioxides As Well As Phenoxazines As Emitters For Oleds PPOX, SMOX, SORD NOX1 458/4885L3MBTL1 2540/4885MEN1 4804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.