Styrene

Styrene

SCHEMBL327472

C=CCOC(=O)C(=C)C=CC(=O)O.C=Cc1ccccc1

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.44
MAPT P10636 4/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
MAPK1 P28482 2/20 0.41
KDM4E B2RXH2 2/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
ALDH1A1 P00352 6/20 0.40
TSHR P16473 3/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HSD17B10 Q99714 2/20 0.39
PKM P14618 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HCAR2 Q8TDS4 3/20 0.39
HDAC3 O15379 1/20 0.39
TNKS O95271 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL7123463 0.86 MEN1 (0.53) MAPTMEN1KMT2AMAPK1KDM4E
SCHEMBL250194 0.84 MAPT (0.38) CYP3A4MAPTMEN1KMT2AMAPK1
Styrene SCHEMBL1255712 0.84 CYP3A4 (0.40) CYP3A4MAPTMEN1KMT2AMAPK1
Styrene SCHEMBL3058331 0.84 HCAR2 (0.53) CYP3A4MAPTMEN1KMT2AMAPK1
SCHEMBL500262 0.84 CYP3A4 (0.51) CYP3A4MAPTMEN1KMT2AMAPK1
Styrene SCHEMBL9551543 0.84 HCAR2 (0.53) CYP3A4MAPTMEN1KMT2AMAPK1
Styrene SCHEMBL327555 0.83 CYP3A4 (0.38) CYP3A4MAPTMEN1KMT2AMAPK1
Styrene SCHEMBL8516972 0.83 HCAR2 (0.44) MAPTMEN1KMT2AKDM4ELMNA
Styrene SCHEMBL9509512 0.83 CYP3A4 (0.50) CYP3A4MAPTMEN1KMT2AMAPK1
Styrene SCHEMBL2539779 0.82 HCAR2 (0.38) MAPTMEN1KMT2AMAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 584 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3266908-B1 ANTI-BACTERIAL METALLO IONOMER POLYMER NANOCOMPOSITE FILAMENTS AND METHODS OF MAKING THE SAME XEROX CORP (US) 2020-05-06 EP claimed
US-10570290-B2 Anti-bacterial aqueous ink compositions comprising metal ion composite ionomer resins XEROX CORPORATION (US) 2020-02-25 US claimed
EP-3266613-B1 ANTI-BACTERIAL METALLO IONOMER POLYMER COMPOSITE POWDERS AND METHODS OF MAKING THE SAME XEROX CORP (US) 2019-10-16 EP claimed
US-10405540-B2 Anti-bacterial metallo ionomer polymer nanocomposite filaments and methods of making the same XEROX CORPORATION (US) 2019-09-10 US claimed
US-10113059-B2 Anti-bacterial metallo ionomer polymer nanocomposite powders and methods of making the same XEROX CORPORATION (US) 2018-10-30 US claimed
US-10067434-B2 Emulsion aggregation toners XEROX CORPORATION (US) 2018-09-04 US claimed
US-10007205-B2 Styrene acrylate hybrid toner process utilizing a low VOC (volatile organic compound) coalescent agent in toner shells XEROX CORPORATION (US) 2018-06-26 US claimed
US-10007200-B2 Antimicrobial toner XEROX CORPORATION (US) 2018-06-26 US claimed
US-9989873-B1 Toner compositions with antiplasticizers comprising purine derivative XEROX CORPORATION (US) 2018-06-05 US claimed
US-20180037750-A1 Anti-Bacterial Aqueous Ink Compositions Comprising Metal Ion Composite Ionomer Resins XEROX CORPORATION 2018-02-08 US claimed
US-5928829-A Latex processes XEROX CORPORATION (US) 1999-07-27 US claimed
US-5928830-A Latex processes XEROX CORPORATION (US) 1999-07-27 US claimed
EP-0928991-A2 Toner preparation processes Xerox Corporation (US) 1999-07-14 EP claimed
US-5869215-A Toner compositions and processes thereof XEROX CORPORATION (US) 1999-02-09 US claimed
US-5863698-A MIXING COLORANT COMPRISING PHOSPHATE-CONTAINING SURFACTANT, LATEX EMULSION, HEATING, STABILIZING XEROX CORPORATION (US) 1999-01-26 US claimed
US-5858601-A Toner processes XEROX CORPORATION (US) 1999-01-12 US claimed
US-5766818-A Toner processes with hydrolyzable surfactant XEROX CORPORATION (US) 1998-06-16 US claimed
US-5766817-A AGGREGATING COLORANT DISPERSION WITH LATEX MINIEMULSION CONTAINING POLYMER AND IONIC AND NONIONIC SURFACTANTS, COALESCING THE AGGREGATES GENERATED XEROX CORPORATION (US) 1998-06-16 US claimed
US-5763133-A Toner compositions and processes XEROX CORPORATION (US) 1998-06-09 US claimed
US-5747215-A Toner compositions and processes XEROX CORPORATION (US) 1998-05-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10113059-B2 Anti-bacterial metallo ionomer polymer nanocomposite powders and methods of making the same RPN1, RPN2, MSH2 CYP3A4 4433/4885MAPT 667/4885MEN1 1372/4885
US-10405540-B2 Anti-bacterial metallo ionomer polymer nanocomposite filaments and methods of making the same TERB1, NBAS, MFAP1 CYP3A4 4575/4885MAPT 159/4885MEN1 1314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.