Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21132537 | 0.77 | KRAS (0.34) | KRASSOS1 | |
| SCHEMBL24343563 | 0.73 | — | — | |
| SCHEMBL23344916 | 0.72 | SOS1 (0.41) | KRASSOS1 | |
| SCHEMBL22827426 | 0.72 | PDK2 (0.37) | KRASSOS1 | |
| SCHEMBL25020196 | 0.72 | BACE1 (0.36) | — | |
| SCHEMBL23995719 | 0.72 | PTGS2 (0.40) | — | |
| SCHEMBL21132431 | 0.70 | SOS1 (0.39) | KRASSOS1 | |
| SCHEMBL28798525 | 0.70 | SOS1 (0.39) | KRASSOS1 | |
| SCHEMBL24801882 | 0.69 | PNMT (0.33) | — | |
| SCHEMBL24802168 | 0.69 | SOS1 (0.36) | KRASSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728254-B1 | BENZYLAMINO SUBSTITUTED PYRIDOPYRIMIDINONES AND DERIVATIVES AS SOS1 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2023-02-15 | — | — | EP | disclosed |