Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.37 |
| ▸ | USP2 | O75604 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30794004 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AKDM4EBRCA1 | |
| SCHEMBL25027695 | 0.89 | LIPE (0.38) | ALDH1A1MEN1KMT2AKDM4EBRCA1 | |
| SCHEMBL30193643 | 0.89 | LIPE (0.38) | ALDH1A1MEN1KMT2AKDM4EBRCA1 | |
| SCHEMBL25027489 | 0.79 | POLB (0.37) | CYP3A4CYP2C9MAP3K11 | |
| SCHEMBL30793990 | 0.79 | POLB (0.37) | CYP3A4CYP2C9MAP3K11 | |
| SCHEMBL25025758 | 0.74 | MMP13 (0.33) | KDM4E | |
| SCHEMBL30193980 | 0.74 | MMP13 (0.33) | KDM4E | |
| SCHEMBL4510903 | 0.74 | CYP1A2 (0.54) | ALDH1A1KDM4ECYP1A2NTRK1IGF1R | |
| SCHEMBL25027490 | 0.74 | GSK3B (0.30) | — | |
| SCHEMBL30793996 | 0.74 | GSK3B (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117751119-A | Potassium channel modulators | 奥蒂福尼疗法有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-117751119-A | Potassium channel modulators | 奥蒂福尼疗法有限公司 | 2024-03-22 | — | — | CN | disclosed |
| WO-2023017263-A1 | POTASSIUM CHANNEL MODULATORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2023-02-16 | — | — | WO | disclosed |