Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25027695 | 1.00 | LIPE (0.38) | LIPEPOLBL3MBTL1EGLN1MAPK1 | |
| SCHEMBL25027486 | 0.89 | ALDH1A1 (0.45) | EGLN1MAPK1ALDH1A1XDHKDM4E | |
| SCHEMBL30794004 | 0.89 | ALDH1A1 (0.45) | EGLN1MAPK1ALDH1A1XDHKDM4E | |
| SCHEMBL30793990 | 0.87 | POLB (0.37) | POLBL3MBTL1KCNH2SCN10ASCN7A | |
| SCHEMBL25027489 | 0.87 | POLB (0.37) | POLBL3MBTL1KCNH2SCN10ASCN7A | |
| SCHEMBL25027700 | 0.84 | LIPE (0.38) | LIPEPOLBL3MBTL1EGLN1MAPK1 | |
| SCHEMBL30794039 | 0.84 | LIPE (0.38) | LIPEPOLBL3MBTL1EGLN1MAPK1 | |
| SCHEMBL25027896 | 0.79 | MAT2A (0.39) | LIPEPOLBL3MBTL1EGLN1MAPK1 | |
| SCHEMBL23927021 | 0.75 | POLB (0.35) | POLBL3MBTL1KCNH2SCN10AALDH1A1 | |
| SCHEMBL25025657 | 0.75 | DRD1 (0.41) | POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117751119-A | Potassium channel modulators | 奥蒂福尼疗法有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-117751119-A | Potassium channel modulators | 奥蒂福尼疗法有限公司 | 2024-03-22 | — | — | CN | disclosed |
| WO-2023017263-A1 | POTASSIUM CHANNEL MODULATORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2023-02-16 | — | — | WO | disclosed |