Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 3/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 4/20 | 0.32 |
| ▸ | BCAT1 | P54687 | 4/20 | 0.32 |
| ▸ | MMP13 | P45452 | 3/20 | 0.32 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30793990 | 1.00 | POLB (0.37) | POLBL3MBTL1DRD1SCN9ASCN10A | |
| SCHEMBL23927021 | 0.88 | POLB (0.35) | POLBL3MBTL1DRD1SCN9ASCN10A | |
| SCHEMBL25027695 | 0.87 | LIPE (0.38) | POLBL3MBTL1SCN9ASCN10ASCN7A | |
| SCHEMBL30193643 | 0.87 | LIPE (0.38) | POLBL3MBTL1SCN9ASCN10ASCN7A | |
| SCHEMBL25025657 | 0.86 | DRD1 (0.41) | POLBL3MBTL1DRD1BCAT2BCAT1 | |
| SCHEMBL30794092 | 0.86 | DRD1 (0.41) | POLBL3MBTL1DRD1BCAT2BCAT1 | |
| SCHEMBL23927076 | 0.82 | TNKS (0.36) | POLBL3MBTL1DRD1SCN9ASCN10A | |
| SCHEMBL15547373 | 0.82 | L3MBTL1 (0.58) | POLBL3MBTL1DRD1SCN9ASCN10A | |
| SCHEMBL25027486 | 0.79 | ALDH1A1 (0.45) | MAP3K11CYP3A4CYP2C9 | |
| SCHEMBL30794004 | 0.79 | ALDH1A1 (0.45) | MAP3K11CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117751119-A | Potassium channel modulators | 奥蒂福尼疗法有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-117751119-A | Potassium channel modulators | 奥蒂福尼疗法有限公司 | 2024-03-22 | — | — | CN | disclosed |
| WO-2023017263-A1 | POTASSIUM CHANNEL MODULATORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2023-02-16 | — | — | WO | disclosed |