Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321170 | 0.87 | CXCL8 (0.54) | CXCL8EPHX1PTGS2HSD17B10ALOX5 | |
| SCHEMBL27304888 | 0.85 | ALDH1A1 (0.40) | CXCL8ALDH1A1KDM4EPTGS2CFTR | |
| SCHEMBL30338418 | 0.83 | PTGS2 (0.52) | CXCL8ALDH1A1KDM4EPTGS2HSD17B10 | |
| SCHEMBL8203180 | 0.83 | PTGS2 (0.42) | CXCL8ALDH1A1KDM4EPTGS2CFTR | |
| SCHEMBL5215577 | 0.83 | PTGS2 (0.52) | CXCL8ALDH1A1KDM4EPTGS2HSD17B10 | |
| SCHEMBL288752 | 0.83 | PTGS2 (0.52) | CXCL8ALDH1A1KDM4EPTGS2HSD17B10 | |
| SCHEMBL59839 | 0.83 | PTGS2 (0.52) | CXCL8ALDH1A1KDM4EPTGS2HSD17B10 | |
| SCHEMBL6405488 | 0.82 | ALDH1A1 (0.38) | CXCL8ALDH1A1KDM4EPTGS2CFTR | |
| SCHEMBL14505423 | 0.82 | ALDH1A1 (0.38) | CXCL8ALDH1A1KDM4EPTGS2CFTR | |
| SCHEMBL11514961 | 0.82 | ALDH1A1 (0.38) | CXCL8ALDH1A1KDM4EPTGS2CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1570 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11633494-B2 | Compounds and compositions for immunotherapy | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2023-04-25 | — | — | US | claimed |
| US-11633495-B2 | Compounds and compositions for immunotherapy | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2023-04-25 | — | — | US | claimed |
| CN-115181164-A | Derivatives of amatoxins and their coupling to cell binding molecules | 杭州多禧生物科技有限公司 | 2022-10-14 | — | — | CN | claimed |
| CN-115124573-A | Novel cytotoxic molecules for use in cell binding molecule-drug conjugates | 杭州多禧生物科技有限公司 | 2022-09-30 | — | — | CN | claimed |
| EP-4056594-A1 | COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY | Birdie Biopharmaceuticals Inc. (KY) | 2022-09-14 | — | — | EP | claimed |
| CN-109689107-B | Derivatives of amatoxins and their coupling to cell binding molecules | 杭州多禧生物科技有限公司 | 2022-08-16 | — | — | CN | claimed |
| US-20220047711-A1 | PHOTOCROSSLINKING PEPTIDES FOR SITE SPECIFIC CONJUGATION TO FC-CONTAINING PROTEINS | GENENTECH, INC. (US) | 2022-02-17 | — | — | US | claimed |
| EP-3894427-A1 | PHOTOCROSSLINKING PEPTIDES FOR SITE SPECIFIC CONJUGATION TO FC-CONTAINING PROTEINS | Genentech, Inc. (US) | 2021-10-20 | — | — | EP | claimed |
| CN-113227119-A | Photocrosslinked peptides for site-specific conjugation to Fc-containing proteins | 基因泰克公司 | 2021-08-06 | — | — | CN | claimed |
| US-10836796-B2 | Derivatives of amanita toxins and their conjugation to a cell binding molecule | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-11-17 | — | — | US | claimed |
| US-20190269789-A1 | COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY | SHANGHAI BIRDIE BIOTECH, INC. (CN) | 2019-09-05 | — | — | US | claimed |
| US-20190269790-A1 | COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY | SHANGHAI BIRDIE BIOTECH, INC. (CN) | 2019-09-05 | — | — | US | claimed |
| US-10328158-B2 | Compounds and compositions for immunotherapy | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2019-06-25 | — | — | US | claimed |
| EP-3041846-B1 | NOVEL CYTOTOXIC AGENTS FOR CONJUGATION OF DRUGS TO CELL BINDING MOLECULE | HANGZHOU DAC BIOTECH CO LTD (CN) | 2018-11-07 | — | — | EP | claimed |
| US-9988408-B2 | Cytotoxic agents for conjugation to a cell binding molecule | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2018-06-05 | — | — | US | claimed |
| WO-2017046658-A1 | DERIVATIVES OF AMANITA TOXINS AND THEIR CONJUGATION TO A CELL BINDING MOLECULE | HANGZHOU DAC BIOTECH CO, LTD (CN) | 2017-03-23 | — | — | WO | claimed |
| US-20160207949-A1 | NOVEL CYTOTOXIC AGENTS FOR CONJUGATION TO A CELL BINDING MOLECULE | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2016-07-21 | — | — | US | claimed |
| EP-3041846-A1 | NOVEL CYTOTOXIC AGENTS FOR CONJUGATION OF DRUGS TO CELL BINDING MOLECULE | Hangzhou Dac Biotech Co., Ltd (CN) | 2016-07-13 | — | — | EP | claimed |
| WO-2015028850-A1 | NOVEL CYTOTOXIC AGENTS FOR CONJUGATION OF DRUGS TO CELL BINDING MOLECULE | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2015-03-05 | — | — | WO | claimed |
| CN-86105641-A | The method for preparing antianaphylaxis and antibronchospasm of N-dibenzyl-diazacyclo alkyl-alkyl-anilide | — | 1987-04-01 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190269790-A1 | COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY | CD47, CD274, TP53 | CXCL8 240/4885EPHX1 1941/4885ALDH1A1 1617/4885 |
| US-11633494-B2 | Compounds and compositions for immunotherapy | CD47, CD274, TP53 | CXCL8 240/4885EPHX1 1941/4885ALDH1A1 1617/4885 |
| US-20160207949-A1 | NOVEL CYTOTOXIC AGENTS FOR CONJUGATION TO A CELL BINDING MOLECULE | PDCD5, CD4, PDCD6 | CXCL8 2669/4885EPHX1 2956/4885ALDH1A1 1947/4885 |
| US-10836796-B2 | Derivatives of amanita toxins and their conjugation to a cell binding molecule | ANTXR2, ANXA5, C3AR1 | CXCL8 2893/4885EPHX1 4171/4885ALDH1A1 4490/4885 |
| US-11633495-B2 | Compounds and compositions for immunotherapy | CD47, CD274, TP53 | CXCL8 240/4885EPHX1 1941/4885ALDH1A1 1617/4885 |
| US-20190269789-A1 | COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY | CD47, CD274, TP53 | CXCL8 240/4885EPHX1 1941/4885ALDH1A1 1617/4885 |
| US-10328158-B2 | Compounds and compositions for immunotherapy | CD47, CD274, TP53 | CXCL8 240/4885EPHX1 1941/4885ALDH1A1 1617/4885 |
| US-20220047711-A1 | PHOTOCROSSLINKING PEPTIDES FOR SITE SPECIFIC CONJUGATION TO FC-CONTAINING PROTEINS | FCGR2A, FCGR3B, DNPEP | CXCL8 3749/4885EPHX1 1785/4885ALDH1A1 3261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.