Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11232270 | 0.98 | FDPS (0.44) | FDPSMTNR1AMPOEGFRSRC | |
| SCHEMBL3790529 | 0.90 | FDPS (0.44) | FDPSMTNR1AMPOKDM4EHDAC3 | |
| Hydrochloric Acid SCHEMBL10784054 | 0.88 | FDPS (0.43) | FDPSMTNR1AMPOKDM4EHDAC3 | |
| SCHEMBL9321175 | 0.87 | MTNR1A (0.47) | MTNR1AMPOEGFRSRCCAPN1 | |
| SCHEMBL89295 | 0.83 | KEAP1 (0.54) | FDPSNR4A2HDAC3HDAC1HDAC2 | |
| SCHEMBL14966254 | 0.82 | FDPS (0.39) | FDPSMTNR1AKDM4EHDAC3HDAC1 | |
| SCHEMBL414288 | 0.82 | IAPP (0.55) | FDPSKDM4EHDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL9297129 | 0.80 | IAPP (0.53) | FDPSKDM4EHDAC3HDAC1HDAC2 | |
| SCHEMBL4764282 | 0.80 | HDAC3 (0.47) | FDPSKDM4EHDAC3HDAC1HDAC2 | |
| SCHEMBL860002 | 0.79 | TAAR1 (0.57) | MTNR1AMPOKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1613 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11633494-B2 | Compounds and compositions for immunotherapy | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2023-04-25 | — | — | US | claimed |
| US-11633495-B2 | Compounds and compositions for immunotherapy | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2023-04-25 | — | — | US | claimed |
| CN-115181164-A | Derivatives of amatoxins and their coupling to cell binding molecules | 杭州多禧生物科技有限公司 | 2022-10-14 | — | — | CN | claimed |
| CN-115124573-A | Novel cytotoxic molecules for use in cell binding molecule-drug conjugates | 杭州多禧生物科技有限公司 | 2022-09-30 | — | — | CN | claimed |
| EP-4056594-A1 | COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY | Birdie Biopharmaceuticals Inc. (KY) | 2022-09-14 | — | — | EP | claimed |
| CN-109689107-B | Derivatives of amatoxins and their coupling to cell binding molecules | 杭州多禧生物科技有限公司 | 2022-08-16 | — | — | CN | claimed |
| US-20220047711-A1 | PHOTOCROSSLINKING PEPTIDES FOR SITE SPECIFIC CONJUGATION TO FC-CONTAINING PROTEINS | GENENTECH, INC. (US) | 2022-02-17 | — | — | US | claimed |
| EP-3894427-A1 | PHOTOCROSSLINKING PEPTIDES FOR SITE SPECIFIC CONJUGATION TO FC-CONTAINING PROTEINS | Genentech, Inc. (US) | 2021-10-20 | — | — | EP | claimed |
| CN-113227119-A | Photocrosslinked peptides for site-specific conjugation to Fc-containing proteins | 基因泰克公司 | 2021-08-06 | — | — | CN | claimed |
| US-10836796-B2 | Derivatives of amanita toxins and their conjugation to a cell binding molecule | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-11-17 | — | — | US | claimed |
| US-20200079820-A1 | DERIVATIVES OF AMANITA TOXINS AND THEIR CONJUGATION TO A CELL BINDING MOLECULE | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-03-12 | — | — | US | claimed |
| US-20190269789-A1 | COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY | SHANGHAI BIRDIE BIOTECH, INC. (CN) | 2019-09-05 | — | — | US | claimed |
| US-20190269790-A1 | COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY | SHANGHAI BIRDIE BIOTECH, INC. (CN) | 2019-09-05 | — | — | US | claimed |
| US-10328158-B2 | Compounds and compositions for immunotherapy | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2019-06-25 | — | — | US | claimed |
| EP-3041846-B1 | NOVEL CYTOTOXIC AGENTS FOR CONJUGATION OF DRUGS TO CELL BINDING MOLECULE | HANGZHOU DAC BIOTECH CO LTD (CN) | 2018-11-07 | — | — | EP | claimed |
| US-9988408-B2 | Cytotoxic agents for conjugation to a cell binding molecule | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2018-06-05 | — | — | US | claimed |
| WO-2017046658-A1 | DERIVATIVES OF AMANITA TOXINS AND THEIR CONJUGATION TO A CELL BINDING MOLECULE | HANGZHOU DAC BIOTECH CO, LTD (CN) | 2017-03-23 | — | — | WO | claimed |
| US-20160207949-A1 | NOVEL CYTOTOXIC AGENTS FOR CONJUGATION TO A CELL BINDING MOLECULE | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2016-07-21 | — | — | US | claimed |
| EP-3041846-A1 | NOVEL CYTOTOXIC AGENTS FOR CONJUGATION OF DRUGS TO CELL BINDING MOLECULE | Hangzhou Dac Biotech Co., Ltd (CN) | 2016-07-13 | — | — | EP | claimed |
| WO-2015028850-A1 | NOVEL CYTOTOXIC AGENTS FOR CONJUGATION OF DRUGS TO CELL BINDING MOLECULE | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2015-03-05 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190269790-A1 | COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY | CD47, CD274, TP53 | FDPS 926/4885MTNR1A 3481/4885MPO 597/4885 |
| US-20200079820-A1 | DERIVATIVES OF AMANITA TOXINS AND THEIR CONJUGATION TO A CELL BINDING MOLECULE | ANTXR2, ANXA5, C3AR1 | FDPS 4044/4885MTNR1A 1179/4885MPO 1131/4885 |
| US-11633494-B2 | Compounds and compositions for immunotherapy | CD47, CD274, TP53 | FDPS 926/4885MTNR1A 3481/4885MPO 597/4885 |
| US-20160207949-A1 | NOVEL CYTOTOXIC AGENTS FOR CONJUGATION TO A CELL BINDING MOLECULE | PDCD5, CD4, PDCD6 | FDPS 4583/4885MTNR1A 2027/4885MPO 3281/4885 |
| US-10836796-B2 | Derivatives of amanita toxins and their conjugation to a cell binding molecule | ANTXR2, ANXA5, C3AR1 | FDPS 3939/4885MTNR1A 1152/4885MPO 1165/4885 |
| US-11633495-B2 | Compounds and compositions for immunotherapy | CD47, CD274, TP53 | FDPS 926/4885MTNR1A 3481/4885MPO 597/4885 |
| US-20190269789-A1 | COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY | CD47, CD274, TP53 | FDPS 926/4885MTNR1A 3481/4885MPO 597/4885 |
| US-10328158-B2 | Compounds and compositions for immunotherapy | CD47, CD274, TP53 | FDPS 926/4885MTNR1A 3481/4885MPO 597/4885 |
| US-20220047711-A1 | PHOTOCROSSLINKING PEPTIDES FOR SITE SPECIFIC CONJUGATION TO FC-CONTAINING PROTEINS | FCGR2A, FCGR3B, DNPEP | FDPS 1240/4885MTNR1A 1753/4885MPO 2152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.