Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5901349 | 0.85 | MME (0.41) | MMEACECPA1ACE2MEN1 | |
| SCHEMBL20047603 | 0.80 | FAAH (0.45) | MMEACECPA1ACE2MEN1 | |
| SCHEMBL20047507 | 0.80 | RIPK1 (0.47) | MMEACECPA1ACE2TSHR | |
| SCHEMBL12308640 | 0.80 | ACE (0.39) | MMEACECPA1ACE2MEN1 | |
| SCHEMBL22271602 | 0.75 | FPR2 (0.39) | ACACBACACAMMEGRNSORT1 | |
| SCHEMBL22271607 | 0.75 | FPR2 (0.39) | ACACBACACAMMEGRNSORT1 | |
| SCHEMBL22251624 | 0.74 | MME (0.39) | MMEACECPA1ACE2MEN1 | |
| SCHEMBL2863541 | 0.74 | MME (0.39) | MMEACECPA1ACE2MEN1 | |
| SCHEMBL2863543 | 0.74 | MME (0.39) | MMEACECPA1ACE2MEN1 | |
| SCHEMBL20013297 | 0.74 | ACACB (0.38) | ACACBACACAMMEACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016346-A1 | POLYPEPTIDE COMPOUND CONTAINING LACTAM BRIDGE | 南京明德新药研发有限公司 | 2023-02-16 | — | — | WO | disclosed |