Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13113388 | 0.92 | CES2 (0.42) | ALDH1A1CES2TSHRTHRBEPHX2 | |
| SCHEMBL11928874 | 0.89 | ALDH1A1 (0.41) | ALDH1A1CES2TSHRTHRBEPHX2 | |
| SCHEMBL12733551 | 0.89 | ALDH1A1 (0.41) | ALDH1A1CES2TSHRTHRBEPHX2 | |
| SCHEMBL72044 | 0.89 | CES2 (0.42) | ALDH1A1CES2TSHRTHRBEPHX2 | |
| SCHEMBL13014736 | 0.89 | ALDH1A1 (0.43) | ALDH1A1CES2TSHRTHRBEPHX2 | |
| SCHEMBL26376485 | 0.87 | CES2 (0.44) | ALDH1A1CES2TSHRMEN1KMT2A | |
| SCHEMBL25516086 | 0.85 | MEN1 (0.46) | ALDH1A1TSHRTHRBEPHX2CASP1 | |
| SCHEMBL15045346 | 0.83 | ALDH1A1 (0.45) | ALDH1A1CES2TSHRTHRBEPHX2 | |
| SCHEMBL19069645 | 0.83 | ALDH1A1 (0.40) | ALDH1A1TSHREPHX2CASP1CASP7 | |
| SCHEMBL25029950 | 0.83 | SMN1; SMN2 (0.40) | ALDH1A1CES2TSHRTHRBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017483-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-02-16 | — | — | WO | disclosed |