Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.45 |
| ▸ | EGFR | P00533 | 4/20 | 0.45 |
| ▸ | ABL2 | P42684 | 4/20 | 0.45 |
| ▸ | SRC | P12931 | 13/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | TEK | Q02763 | 2/20 | 0.43 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.42 |
| ▸ | AHCY | P23526 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047877 | 0.84 | AHCY (0.61) | ABL1EGFRABL2METTL3AHCY | |
| SCHEMBL31617987 | 0.84 | AHCY (0.61) | ABL1EGFRABL2METTL3AHCY | |
| SCHEMBL25047444 | 0.78 | AHCY (0.46) | ABL1EGFRABL2SRCMETTL3 | |
| SCHEMBL24040352 | 0.73 | HIF1A (0.51) | METTL3ADK | |
| SCHEMBL20917263 | 0.71 | ADK (0.47) | METTL3RAB9AADK | |
| SCHEMBL20938188 | 0.71 | ADK (0.47) | METTL3RAB9AADK | |
| SCHEMBL31618064 | 0.71 | METTL3 (0.49) | METTL3AHCY | |
| SCHEMBL25048822 | 0.71 | METTL3 (0.49) | METTL3AHCY | |
| SCHEMBL30941392 | 0.71 | METTL3 (0.49) | METTL3AHCY | |
| SCHEMBL25048765 | 0.67 | METTL3 (0.66) | ABL1EGFRABL2METTL3AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |