Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | NMT2 | O60551 | 2/20 | 0.49 |
| ▸ | NMT1 | P30419 | 2/20 | 0.49 |
| ▸ | CHRND | Q07001 | 6/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.47 |
| ▸ | CHRNG | P07510 | 2/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25062576 | 0.90 | NMT1 (0.48) | SIRT6SIRT1TLR2NMT2NMT1 | |
| SCHEMBL25062579 | 0.90 | NMT1 (0.46) | SIRT6SIRT1TLR2NMT2NMT1 | |
| SCHEMBL254293 | 0.86 | SIRT6 (0.48) | SIRT6SIRT1TLR2NMT2NMT1 | |
| SCHEMBL17325767 | 0.86 | SIRT6 (0.48) | SIRT6SIRT1TLR2NMT2NMT1 | |
| SCHEMBL18893551 | 0.85 | SIRT6 (0.50) | SIRT6SIRT1TLR2 | |
| SCHEMBL16152402 | 0.85 | GLP1R (0.41) | NMT2NMT1 | |
| SCHEMBL18932369 | 0.83 | NMT1 (0.47) | SIRT6SIRT1TLR2NMT2NMT1 | |
| SCHEMBL7996266 | 0.83 | SLC6A5 (0.50) | — | |
| SCHEMBL16152399 | 0.82 | ROCK2 (0.48) | TLR2NMT2NMT1 | |
| SCHEMBL29467596 | 0.81 | GLP1R (0.47) | SIRT6SIRT1TLR2NMT2NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230057350-A1 | A CONJUGATE OF AN AMANITA TOXIN WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230057350-A1 | A CONJUGATE OF AN AMANITA TOXIN WITH BRANCHED LINKERS | BTN3A1, ANTXR2, CLTA | SIRT6 4274/4885SIRT1 4799/4885TLR2 976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.