SCHEMBL16152402

O=C(CCCN1C(=O)C=CC1=O)NCCCC[C@H](NC(=O)CCCN1C(=O)C=CC1=O)C(=O)NCCNC(=O)[C@H](CCCCNC(=O)CCCN1C(=O)C=CC1=O)NC(=O)CCCN1C(=O)C=CC1=O

nearest known ligand 0.41

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	8/20	0.41

▸	NMT2	O60551	1/20	0.38

▸	NMT1	P30419	1/20	0.38

▸	SIRT2	Q8IXJ6	2/20	0.38

▸	FOLH1	Q04609	1/20	0.38

▸	PTGS1	P23219	4/20	0.38

▸	PTGS2	P35354	4/20	0.38

▸	ROCK2	O75116	2/20	0.38

▸	AKT1	P31749	1/20	0.38

▸	PRKACA	P17612	1/20	0.38

▸	AKT3	Q9Y243	1/20	0.38

▸	ALB	P02768	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16152399	0.91	ROCK2 (0.48)	NMT2NMT1ROCK2PRKACAAKT3
SCHEMBL16152405	0.89	ROCK2 (0.51)	NMT2NMT1ROCK2PRKACAAKT3
SCHEMBL22389098	0.89	ALB (0.47)	GLP1RFOLH1PTGS1PTGS2ALB
SCHEMBL16152421	0.88	ALB (0.48)	FOLH1PTGS1PTGS2ROCK2PRKACA
SCHEMBL17325767	0.86	SIRT6 (0.48)	NMT2NMT1ROCK2PRKACAAKT3
SCHEMBL254293	0.86	SIRT6 (0.48)	NMT2NMT1ROCK2PRKACAAKT3
SCHEMBL12284049	0.86	GLP1R (0.39)	GLP1RNMT2NMT1SIRT2FOLH1
SCHEMBL24983625	0.85	NMT2 (0.41)	GLP1RNMT2NMT1PTGS1PTGS2
SCHEMBL25062575	0.85	SIRT6 (0.53)	NMT2NMT1
SCHEMBL12946729	0.84	NOD1 (0.49)	GLP1RPTGS1PTGS2ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2786766-A1	Supramolecular aggregates comprising maleimido cores	Ufpeptides S.r.l. (IT)	2014-10-08	—	—	EP	disclosed