Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5345377 | 0.82 | FAAH (0.33) | ALDH1A1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL4967939 | 0.76 | SSTR4 (0.48) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL17165003 | 0.76 | — | — | |
| SCHEMBL12425624 | 0.74 | CYP2D6 (0.50) | CYP2D6CYP2C19ALDH1A1EPHX1MMP1 | |
| SCHEMBL6925234 | 0.73 | — | — | |
| SCHEMBL2502811 | 0.72 | TSHR (0.46) | ALDH1A1SMN1; SMN2KDM4ETP53HTT | |
| SCHEMBL16408013 | 0.72 | ALDH1A1 (0.46) | CYP2D6CYP2C19ALDH1A1NPC1HPGD | |
| SCHEMBL9639095 | 0.71 | — | — | |
| SCHEMBL2504415 | 0.71 | — | — | |
| SCHEMBL9639090 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718630-B2 | Compositions and methods for treating cancer | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-08-08 | — | — | US | disclosed |
| US-20230135350-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-04 | — | — | US | disclosed |
| US-11208388-B2 | Certain chemical entities, compositions, and methods | NEUPHARMA, INC (US) | 2021-12-28 | — | — | US | disclosed |
| US-20190322958-A1 | Lubricant Composition | BASF SE (DE) | 2019-10-24 | — | — | US | disclosed |
| EP-2553059-B1 | LUBRICATING OIL COMPOSITIONS CONTAINING EPOXIDE ANTIWEAR AGENTS | CHEVRON ORONITE CO (US) | 2019-10-23 | — | — | EP | disclosed |
| US-10066186-B2 | Lubricating oil compositions containing a halide seal compatibility additive and a second seal compatibility additive | BASF SE (DE) | 2018-09-04 | — | — | US | disclosed |
| WO-2018089416-A1 | LUBRICANT COMPOSITION | BASF SE (DE) | 2018-05-17 | — | — | WO | disclosed |
| US-9677023-B2 | Lubricating oil compositions containing seal compatibility additives and sterically hindered amines | BASF SE (DE) | 2017-06-13 | — | — | US | disclosed |
| EP-3129454-A1 | LUBRICATING OIL COMPOSITIONS CONTAINING SEAL COMPATIBILITY ADDITIVES AND STERICALLY HINDERED AMINES | BASF SE (DE) | 2017-02-15 | — | — | EP | disclosed |
| US-20170029737-A1 | LUBRICANT COMPOSITIONS COMPRISING EPOXIDE COMPOUNDS | BASF SE (DE) | 2017-02-02 | — | — | US | disclosed |
| US-20140142011-A1 | Lubricant Compositions Comprising Epoxide Compounds | BASF SE | 2014-05-22 | — | — | US | disclosed |
| US-20140142010-A1 | Lubricant Compositions Comprising Epoxide Compounds | BASF SE | 2014-05-22 | — | — | US | disclosed |
| WO-2014078712-A1 | LUBRICANT COMPOSITIONS COMPRISING EPOXIDE COMPOUNDS TO IMPROVE FLUOROPOLYMER SEAL COMPATIBILITY | BASF SE (DE) | 2014-05-22 | — | — | WO | disclosed |
| US-20140142009-A1 | Lubricant Compositions Comprising Epoxide Compounds | BASF SE | 2014-05-22 | — | — | US | disclosed |
| US-20140038869-A1 | LUBRICATING OIL COMPOSITIONS CONTAINING EPOXIDE ANTIWEAR AGENTS | CHEVRON ORONITE COMPANY LLC (US) | 2014-02-06 | — | — | US | disclosed |
| US-20130281333-A1 | LUBRICATING OIL COMPOSITIONS CONTAINING EPOXIDE ANTIWEAR AGENTS | CHEVRON ORONITE COMPANY LLC (US) | 2013-10-24 | — | — | US | disclosed |
| US-8486873-B2 | Lubricating oil compositions containing epoxide antiwear agents | CHEVRON ORONITE COMPANY LLC (US) | 2013-07-16 | — | — | US | disclosed |
| EP-2553059-A2 | LUBRICATING OIL COMPOSITIONS CONTAINING EPOXIDE ANTIWEAR AGENTS | Chevron Oronite Company LLC (US) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011126636-A2 | LUBRICATING OIL COMPOSITIONS CONTAINING EPOXIDE ANTIWEAR AGENTS | CHEVRON ORONITE COMPANY LLC (US) | 2011-10-13 | — | — | WO | disclosed |
| US-20110239969-A1 | LUBRICATING OIL COMPOSITIONS CONTAINING EPOXIDE ANTIWEAR AGENTS | CHEVRON ORONITE COMPANY LLC | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230135350-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | KRAS, HRAS, NRAS | CYP2D6 4817/4885CYP2C19 4848/4885ALDH1A1 2792/4885 |
| US-11718630-B2 | Compositions and methods for treating cancer | KRAS, HRAS, NRAS | CYP2D6 4817/4885CYP2C19 4848/4885ALDH1A1 2792/4885 |
| US-11208388-B2 | Certain chemical entities, compositions, and methods | BRAF, PIK3CA, PLK1 | CYP2D6 1933/4885CYP2C19 1047/4885ALDH1A1 1767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.