SCHEMBL5345377

SCHEMBL5345377

CCC(C)CNC(=O)C1CO1

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
NAMPT P43490 2/20 0.32
HPGD P15428 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
ALDH1A1 P00352 2/20 0.32
CTSD P07339 2/20 0.31
BCHE P06276 1/20 0.30
HRH4 Q9H3N8 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2506531 0.82 CYP2D6 (0.46) HPGDSMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL10592638 0.82 TDP1 (0.49) HPGDSMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL2502811 0.75 TSHR (0.46) SMN1; SMN2ALDH1A1HRH4HRH3
SCHEMBL13460017 0.74 HTT (0.39) FAAHCNR1CNR2NAMPTHPGD
SCHEMBL23638026 0.73 ALDH1A1 (0.34) FAAHCNR1CNR2NAMPTALDH1A1
SCHEMBL2502163 0.72
SCHEMBL23236466 0.71 ALDH1A1 (0.46) FAAHCNR1CNR2ALDH1A1CTSD
SCHEMBL20888367 0.71 ALDH1A1 (0.46) FAAHCNR1CNR2ALDH1A1CTSD
SCHEMBL2820655 0.71 EPHX1 (0.45) FAAHCNR1CNR2NAMPTHRH4
SCHEMBL15716575 0.69 BCHE (0.56) HPGDSMN1; SMN2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312266-B2 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers THE COLLEGE OF WILLIAM AND MARY (US) 2007-12-25 US disclosed
US-7109261-B2 Latent mercaptans as multi-functional additives for halogen-containing polymer compositions ROHM AND HAAS COMPANY (US) 2006-09-19 US disclosed
US-7105109-B2 Latent mercaptans as stabilizers for halogen-containing polymer compositions ROHM AND HAAS COMPANY (US) 2006-09-12 US disclosed
US-7025904-B2 Method for improving adhesion of water-based inks to halogen-containing resin articles ROHM AND HAAS COMPANY (US) 2006-04-11 US disclosed
EP-1055704-B1 Method for improving adhesion of water based inks to halogen containing resin articles ROHM & HAAS (US) 2005-11-23 EP disclosed
EP-1571178-A2 Method for improving adhesion of water-based inks to halogen-containing resin articles ROHM AND HAAS COMPANY (US) 2005-09-07 EP disclosed
US-20050176862-A1 Latent mercaptans as multi-functional additives for halogen-containing polymer compositions PMC CINCINNATI, INC. 2005-08-11 US disclosed
US-6927247-B2 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers THE COLLEGE OF WILLIAM AND MARY (US) 2005-08-09 US disclosed
EP-1521803-A2 ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS The College of William and Mary (US) 2005-04-13 EP disclosed
US-20050049307-A1 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers COLLEGE OF WILLIAM AND MARY, THE 2005-03-03 US disclosed
EP-0945484-A1 Synergistic blend of a metal-based stabilizer or Lewis acid and a free mercaptan for enhanced PVC stabilization MORTON INTERNATIONAL, INC. (US) 1999-09-29 EP disclosed
EP-0945485-A1 A latent mercaptan as a heat stabilizer MORTON INTERNATIONAL, INC. (US) 1999-09-29 EP disclosed
EP-0890608-A2 A latent mercaptan as a heat stabilizer MORTON INTERNATIONAL, INC. (US) 1999-01-13 EP disclosed
EP-0742259-A1 Latent mercaptans as multi-functional additives for halogen-containing polymer compositions MORTON INTERNATIONAL, INC. (US) 1996-11-13 EP disclosed
US-4342875-A STABILIZERS FOR OLEFIN POLYMERS CINCINNATI-MILACRON, INC. (US) 1982-08-03 US disclosed
US-RE29523-E Olefinic polymers stabilized with thioacyl trivalent phosphorus compounds BORG-WARNER CORPORATION (US) 1978-01-24 US disclosed
US-4064100-A HEAT AND LIGHT STABILIZERS FOR POLYMERS, CONTAINERS FOR FOOD WESTON CHEMICAL CO., INC. (US) 1977-12-20 US disclosed
US-4012399-A ULTRAVIOLET LIGHT ABSORBERS AND STABILIZERS CINCINNATI MILACRON CHEMICALS, INC. (US) 1977-03-15 US disclosed
US-4000101-A POLYPROPYLENE WESTON CHEMICAL CORPORATION (US) 1976-12-28 US disclosed
US-3959220-A Polymer additives comprising transition metal complexes with trivalent phosphorous compounds CINCINNATI MILACRON CHEMICALS, INC. (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050049307-A1 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers TST, LANCL1, TTPA FAAH 3999/4885CNR1 4554/4885CNR2 4656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.