Phenglutarimide

Phenglutarimide

SCHEMBL250700

CCN(CC)CCC1(c2ccccc2)CCC(=O)NC1=O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 18/20 0.56
ALDH1A1 P00352 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP3A4 P08684 2/20 0.51
CYP17A1 P05093 1/20 0.51
CYP11A1 P05108 1/20 0.51
TBXAS1 P24557 1/20 0.51
PMP22 Q01453 1/20 0.51
PDE4D Q08499 1/20 0.51
PDE3A Q14432 1/20 0.51
NFKB1 P19838 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenglutarimide SCHEMBL1649930 0.97 CYP19A1 (0.56) CYP19A1ALDH1A1CYP1A2CYP2D6
Glutethimide SCHEMBL113709 0.82 CYP19A1 (0.72) CYP19A1ALDH1A1CYP1A2CYP2D6CYP3A4
Glutethimide SCHEMBL21119240 0.82 CYP19A1 (0.72) CYP19A1ALDH1A1CYP1A2CYP2D6CYP3A4
Glutethimide SCHEMBL113708 0.82 CYP19A1 (0.72) CYP19A1ALDH1A1CYP1A2CYP2D6CYP3A4
SCHEMBL11847657 0.77 ALDH1A1 (0.54) CYP19A1ALDH1A1CYP1A2CYP2D6
Glutethimide SCHEMBL28781825 0.76 CYP19A1 (0.63) CYP19A1ALDH1A1CYP1A2CYP2D6CYP3A4
SCHEMBL17471628 0.76 CYP19A1 (0.53) CYP19A1ALDH1A1
SCHEMBL6246501 0.75 CYP19A1 (0.52) CYP19A1ALDH1A1CYP1A2CYP2D6CYP3A4
Hydrochloric Acid SCHEMBL10920499 0.75 SIGMAR1 (0.43) ALDH1A1
SCHEMBL11929003 0.74 SIGMAR1 (0.40) ALDH1A1CYP1A2CYP2D6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4154879-B1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NICOTINE WITHDRAWAL SYMPTOMS KOREA INST SCI & TECH (KR) 2025-09-10 EP claimed
WO-2025038382-A1 PHARMACEUTICAL ADHESIVE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2025-02-20 WO claimed
WO-2024218296-A1 COMBINATION TREATMENTS COMPRISING ADMINISTRATION OF LEUCINE-RICH REPEAT KINASE 2 (LRRK2) INHIBITORS H. LUNDBECK A/S (DK) 2024-10-24 WO claimed
EP-4154879-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NICOTINE WITHDRAWAL SYMPTOMS Korea Institute of Science and Technology (KR) 2023-03-29 EP claimed
EP-3852608-A1 COMPOSITIONS AND METHODS FOR GLAUCOMA Aufbau Medical Innovations Limited (IE) 2021-07-28 EP claimed
US-10987316-B2 Compositions and methods for transdermal delivery of tertiary amine drugs NOVEN PHARMACEUTICALS, INC. (US) 2021-04-27 US claimed
WO-2020061550-A1 COMPOSITIONS AND METHODS FOR GLAUCOMA AUFBAU MEDICAL INNOVATIONS LIMITED (IE) 2020-03-26 WO claimed
US-10406116-B2 Pressure-sensitive adhesives for transdermal drug delivery NOVEN PHARMACEUTICALS, INC. (US) 2019-09-10 US claimed
EP-3506889-A1 PRESSURE-SENSITIVE ADHESIVES FOR TRANSDERMAL DRUG DELIVERY Noven Pharmaceuticals, INC. (US) 2019-07-10 EP claimed
WO-2018026759-A1 PRESSURE-SENSITIVE ADHESIVES FOR TRANSDERMAL DRUG DELIVERY NOVEN PHARMACEUTICALS, INC. (US) 2018-02-08 WO claimed
EP-1829527-A2 Aggregate with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin IDEA AG (DE) 2007-09-05 EP claimed
EP-1815846-A2 Aggregate with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin IDEA AG (DE) 2007-08-08 EP claimed
EP-1815847-A2 Aggregate with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin IDEA AG (DE) 2007-08-08 EP claimed
CN-1703199-A Aggregate with enhanced deformability comprising at least three amphiphiles for improved transport through a semi-permeable barrier and use of non-invasive drugs in vivo, in particular through the skin IDEA AG (DE) 2005-11-30 CN claimed
EP-1551370-A1 AGGREGATE WITH INCREASED DEFORMABILITY, COMPRISING AT LEAST THREE AMPHIPATS, FOR IMPROVED TRANSPORT THROUGH SEMI-PERMEABLE BARRIERS AND FOR THE NON-INVASIVE DRUG APPLICATION IN VIVO, ESPECIALLY THROUGH THE SKIN IDEA AG (DE) 2005-07-13 EP claimed
US-20040105881-A1 Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin IDEA AG (DE) 2004-06-03 US claimed
WO-2004032900-A1 AGGREGATE WITH INCREASED DEFORMABILITY, COMPRISING AT LEAST THREE AMPHIPATS, FOR IMPROVED TRANSPORT THROUGH SEMI-PERMEABLE BARRIERS AND FOR THE NON-INVASIVE DRUG APPLICATION IN VIVO, ESPECIALLY THROUGH THE SKIN IDEA AG (DE) 2004-04-22 WO claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040105881-A1 Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin CUTA, ABCG2, PIGS CYP19A1 3028/4885ALDH1A1 2042/4885CYP1A2 1571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.