Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 4/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25076345 | 1.00 | HTR2A (0.39) | HTR2ARETSIGMAR1IDO1PLAU | |
| SCHEMBL25076280 | 1.00 | HTR2A (0.39) | HTR2ARETSIGMAR1IDO1PLAU | |
| SCHEMBL25076414 | 0.81 | SIGMAR1 (0.41) | HTR2ARETSIGMAR1 | |
| SCHEMBL25076434 | 0.80 | KDM1A (0.33) | HTR2AIDO1 | |
| SCHEMBL25076290 | 0.76 | SIGMAR1 (0.41) | HTR2ARETSIGMAR1IDO1 | |
| SCHEMBL25076341 | 0.75 | SIGMAR1 (0.33) | HTR2ARETSIGMAR1 | |
| SCHEMBL18045643 | 0.74 | HTR2A (0.45) | HTR2ARETSIGMAR1IDO1 | |
| SCHEMBL30096678 | 0.74 | HTR2A (0.45) | HTR2ARETSIGMAR1IDO1 | |
| SCHEMBL23832807 | 0.74 | HTR2A (0.45) | HTR2ARETSIGMAR1IDO1 | |
| SCHEMBL25761550 | 0.73 | MTNR1A (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023594-A9 | 2‑DIARYLMETHYL‑4‑AMINOTETRAHYDROPYRAN DERIVATIVES AND RELATED COMPOUNDS AS ANTICANCER, ANTIINFLAMMATORY, ANTIFIBROTIC AND NEUROPROTECTIVE AGENTS | ATUX ISKAY LLC (US) | 2023-06-08 | — | — | WO | disclosed |
| WO-2023023594-A1 | 2‑DIARYLMETHYL‑4‑AMINOTETRAHYDROPYRAN DERIVATIVES AND RELATED COMPOUNDS AS ANTICANCER, ANTIINFLAMMATORY, ANTIFIBROTIC AND NEUROPROTECTIVE AGENTS | ATUX ISKAY LLC (US) | 2023-02-23 | — | — | WO | disclosed |