Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.32 |
| ▸ | ACP3 | P15309 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25076342 | 0.75 | HTR2A (0.39) | SIGMAR1RETHTR2A | |
| SCHEMBL25076345 | 0.75 | HTR2A (0.39) | SIGMAR1RETHTR2A | |
| SCHEMBL25076280 | 0.75 | HTR2A (0.39) | SIGMAR1RETHTR2A | |
| SCHEMBL25076414 | 0.75 | SIGMAR1 (0.41) | SIGMAR1RETHTR2A | |
| SCHEMBL25076290 | 0.69 | SIGMAR1 (0.41) | SIGMAR1ACP3RETHTR2A | |
| SCHEMBL17029485 | 0.69 | TSHR (0.40) | CYP1B1CYP1A1CYP1A2 | |
| SCHEMBL23832807 | 0.68 | HTR2A (0.45) | SIGMAR1ACP3RETHTR2A | |
| SCHEMBL18045643 | 0.68 | HTR2A (0.45) | SIGMAR1ACP3RETHTR2A | |
| SCHEMBL30096678 | 0.68 | HTR2A (0.45) | SIGMAR1ACP3RETHTR2A | |
| SCHEMBL25076340 | 0.67 | MTNR1A (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023594-A9 | 2‑DIARYLMETHYL‑4‑AMINOTETRAHYDROPYRAN DERIVATIVES AND RELATED COMPOUNDS AS ANTICANCER, ANTIINFLAMMATORY, ANTIFIBROTIC AND NEUROPROTECTIVE AGENTS | ATUX ISKAY LLC (US) | 2023-06-08 | — | — | WO | disclosed |
| WO-2023023594-A1 | 2‑DIARYLMETHYL‑4‑AMINOTETRAHYDROPYRAN DERIVATIVES AND RELATED COMPOUNDS AS ANTICANCER, ANTIINFLAMMATORY, ANTIFIBROTIC AND NEUROPROTECTIVE AGENTS | ATUX ISKAY LLC (US) | 2023-02-23 | — | — | WO | disclosed |